Gianotti-Crosti syndrome

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Synonym(s)

Papular acrodermatitis of childhood; papulovesicular acrolocated syndrome; acropapulo-vesicular syndrome; infantile papular acrodermatitis; infantile lichenoid acrodermatitis; erythemato-papulous acrodermatitis; erythemato-vesiculo-papulous eruptive syndrome; acrodermatitis papulosa eruptiva infantilis; papular infantile acrodermatitis; acrodermatitis papulosa infantum; infantile eruptive papulous dermatitis

Definition

Self-limited, childhood exanthem occurring in characteristic distribution and associated with multiple infectious agents

Pathogenesis

Associated with mostly viral agents, including hepatitis B, Epstein-Barr virus (EBV), respiratory syncytial virus (RSV), coxsackievirus and other enteroviruses, parainfluenza virus, parvovirus B19, poxvirus, cytomegalovirus (CMV), human herpesvirus 6 (HHV-6); some occurrences follow immunization with measles-mumps-rubella, poliovirus, and influenza virus vaccines

Clinical manifestation