Definition
Endogenous nucleoside made up of the purinic base adenine and the pentose carbohydrate ribose linked through an N-9 bound. Adenosine is present in all mammalian tissues at both the intra- and extracellular level, and takes part in important physiopathological phenomena (e.g., modulation of inflammation, regulation of heart rhythm). At the level of the central nervous system, adenosine promotes a generalized inhibition of neuronal functionality, a reason why it is often referred to as “endogenous neurodepressant.”
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© 2010 Springer-Verlag Berlin Heidelberg
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Simola, N., Morelli, M. (2010). Adenosine. In: Stolerman, I.P. (eds) Encyclopedia of Psychopharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68706-1_1101
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DOI: https://doi.org/10.1007/978-3-540-68706-1_1101
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-68698-9
Online ISBN: 978-3-540-68706-1
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