2013

Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays

Editors:

ISBN: 978-3-642-25239-6 (Print) 978-3-642-25240-2 (Online)

Table of contents (55 entries)

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  1. Front Matter

    Pages 1-24

  2. Part 1 Safety Pharmacology

    1. Front Matter

      Pages 1-1

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      Pages 3-4

      Safety Pharmacology: Introduction

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      Pages 5-16

      Status of Safety Pharmacology and Present Guidelines

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      Pages 17-72

      Central Nervous System (CNS) Safety Pharmacology Studies

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      Pages 73-97

      Methods in Cardiovascular Safety Pharmacology

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      Pages 99-184

      Renal System in Safety Pharmacology

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      Pages 185-197

      Respiratory Function Assays in Safety Pharmacology

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      Pages 199-255

      Safety Pharmacology in Metabolism Pharmacology

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      Pages 257-275

      Peripheral Nervous System

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      Pages 277-285

      Safety of Intravenous and Inhalation Anesthetics

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      Pages 287-310

      Drug-Addiction and Drug-Dependency

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      Pages 311-391

      Blood Constituents and Safety Pharmacology

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      Pages 393-400

      Ocular Safety Tests

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      Pages 401-419

      Side Effects of Central Analgesic Drugs

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      Pages 421-520

      Endocrine Pharmacology

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      Pages 521-554

      Skin Pharmacology

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      Pages 555-560

      Safety Pharmacology Assessment of Biopharmaceuticals

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      Pages 561-571

      Magnetic Resonance Imaging in Pharmaceutical Safety Assessment

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      Pages 573-593

      Oncology Pharmacology

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      Pages 595-603

      Transgenic Animals

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      Pages 605-629

      Zebrafish in Drug Discovery: Safety Assessment

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