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Animal Cell Biotechnology pp 145–153Cite as

Monitoring Animal Cell Growth and Productivity by Flow Cytometry

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Part of the book series: Methods in Biotechnology™ ((MIBT,volume 8))

Abstract

Flow cytometry provides a rapid and accurate means of analyzing individual cells in suspension. Several parameters can be detected simultaneously and analyzed to provide information on the relationship between them. Fluorescently labeled cells can give quantitative data on specific target molecules and their distribution in the cell population. Moreover, subpopulations of cells with specific attributes can be discriminated and physically sorted for further development. These advantages have given flow cytometry the potential to be applied at all stages of process development, from cell line selection to the development of monitoring and control strategies for animal cell bioreactor operation.

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References

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Author information

Authors and Affiliations

  1. Department of Biochemical Engineering, Birmingham University, Birmingham, UK

    Mohamed Al-Rubeai

Authors
  1. Mohamed Al-Rubeai
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Editor information

Editors and Affiliations

  1. Bioprocess Research and Development, Eli Lilly & Co., Indianapolis, IN

    Nigel Jenkins

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© 1999 Humana Press Inc., Totowa, NJ

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Al-Rubeai, M. (1999). Monitoring Animal Cell Growth and Productivity by Flow Cytometry. In: Jenkins, N. (eds) Animal Cell Biotechnology. Methods in Biotechnology™, vol 8. Humana Press. https://doi.org/10.1385/0-89603-547-6:145

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  • DOI: https://doi.org/10.1385/0-89603-547-6:145

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-547-8

  • Online ISBN: 978-1-59259-486-3

  • eBook Packages: Springer Protocols

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