Protocol

Receptor Binding Techniques

Volume 106 of the series Methods in Molecular Biology pp 139-185

Analysis of Binding Data

  • Edward C. HulmeAffiliated withDivision of Physical Biochemistry, National Institute for Medical Research

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Abstract

A receptor is an allosteric macromolecule (usually associated with a particular cell type) that binds a specific chemical substance (usually secreted by another cell) and in the process undergoes a defined conformational change that triggers a series of biochemical and physiological events within the target cell.