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Hormone Assays in Biological Fluids pp 277–289Cite as

Internal Quality Control

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 1065))

Abstract

Internal quality control (IQC) is a valuable technique to ensure that the results produced from any assay are reliable and reproducible. Here I describe how to set up an IQC program for a new clinical assay based on IQC samples. The principles described here are applicable to assays for any biological material.

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References

  1. CLSI (2011) Laboratory quality control based on risk management; approved guideline. CLSI document EP23-A. Clinical and Laboratory Standards Institute, Wayne, PA

    Google Scholar 

  2. CLSI (2008) User protocol for evaluation of qualitative test performance; approved guideline. CLSI document EP12-A2. Clinical and Laboratory Standards Institute, Wayne, PA

    Google Scholar 

  3. Green GA et al (1997) Quality control for qualitative assays: quantitative procedure designed to assure analytical quality required for an ELISA of hepatitis B surface antigen. Clin Chem 43:1618–1621

    PubMed  CAS  Google Scholar 

  4. CLSI (2004) Evaluation of precision performance of quantitative measurement methods; approved guideline. CLSI document EP5-A2. Clinical and Laboratory Standards Institute, Wayne, PA

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  5. Westgard JO et al (1981) A multi-rule Shewart chart for quality control in clinical chemistry. Clin Chem 27:493–501

    PubMed  CAS  Google Scholar 

  6. Westgard JO et al (1977) Performance characteristics of rules for internal quality control: probabilities for false rejection and error detection. Clin Chem 23:1857–1867

    PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Clinical Chemistry, Queen Elizabeth the Queen Mother Hospital, Margate, Kent, UK

    Edward Kearney

Authors
  1. Edward Kearney
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Editor information

Editors and Affiliations

  1. Consultant Clinical Scientist The Old Dairy, Exmouth, United Kingdom

    Michael J. Wheeler

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© 2013 Springer Science+Business Media New York

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Kearney, E. (2013). Internal Quality Control. In: Wheeler, M. (eds) Hormone Assays in Biological Fluids. Methods in Molecular Biology, vol 1065. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-616-0_18

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  • DOI: https://doi.org/10.1007/978-1-62703-616-0_18

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-615-3

  • Online ISBN: 978-1-62703-616-0

  • eBook Packages: Springer Protocols

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