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Evaluation of IL-2-Withdrawal-Induced Apoptosis in Human T Lymphocytes

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Immune Homeostasis

Part of the book series: Methods in Molecular Biology ((MIMB,volume 979))

Abstract

Proper lymphocyte apoptosis is critical for the maintenance of immune system homeostasis, and evaluation of cell death is useful in a number of clinical and research settings. We describe here how to evaluate the integrity of the intrinsic pathway of lymphocyte apoptosis triggered by starvation for IL-2 or other survival cytokines.

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Correspondence to Joao Bosco Oliveira .

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© 2013 Springer Science+Business Media New York

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Oliveira, J.B. (2013). Evaluation of IL-2-Withdrawal-Induced Apoptosis in Human T Lymphocytes. In: Snow, A., Lenardo, M. (eds) Immune Homeostasis. Methods in Molecular Biology, vol 979. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-290-2_3

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  • DOI: https://doi.org/10.1007/978-1-62703-290-2_3

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-289-6

  • Online ISBN: 978-1-62703-290-2

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