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Bioinformatics for Comparative Proteomics

Volume 694 of the series Methods in Molecular Biology pp 49-61

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Reactome Knowledgebase of Human Biological Pathways and Processes

  • Peter D’EustachioAffiliated withDepartment of Biochemistry, New York University School of Medicine

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Abstract

The Reactome Knowledgebase is an online, manually curated resource that provides an integrated view of the molecular details of human biological processes that range from metabolism to DNA replication and repair to signaling cascades. Its data model allows these diverse processes to be represented in a consistent way to facilitate usage as online text and as a resource for data mining, modeling, and analysis of large-scale expression data sets over the full range of human biological processes.

Key words

BioMart Data aggregation Gene ontology High-throughput expression data Pathway analysis