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Tissue Engineering pp 167–182Cite as

Artificial Skin

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Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 140))

Summary

Replacement of skin has been one of the most challenging aims for surgeons ever since the introduction of skin grafts in 1871. It took more than one century until the breakthrough of Rheinwald and Green in 1975 that opened new possibilities of skin replacement. The combination of cell culture and polymer chemistry finally led to the field of tissue engineering. Many researchers all over the world have been fascinated by the chance of creating a skin-like substitute ex vivo without any further harm to the patients, especially those with massive burns. Many different approaches to create new substitutes and further improvements in genetical and stem cell research led to today’s skin equivalents. But still, the “gold standard” for wound coverage is the autologous split-thickness skin graft. Future research will aim at originating biologically and physiologically equal skin substitutes for the treatment of severe burns and chronic ulcers.

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Author information

Authors and Affiliations

  1. Department of Plastic and Hand Surgery, University of Freiburg Medical Center, Freiburg i. Br., Germany

    M. Föhn & H. Bannasch

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  1. M. Föhn
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  2. H. Bannasch
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Editor information

Editors and Affiliations

  1. Department of Gene Regulation and Differentiation, National Research Center for Biotechnology GBF, Braunschweig, Germany

    Hansjörg Hauser

  2. Institute for Chemical and Bio-Engineering, ETH Zurich, Zurich, Switzerland

    Martin Fussenegger

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© 2007 Humana Press Inc.

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Föhn, M., Bannasch, H. (2007). Artificial Skin. In: Hauser, H., Fussenegger, M. (eds) Tissue Engineering. Methods in Molecular Medicine™, vol 140. Humana Press. https://doi.org/10.1007/978-1-59745-443-8_10

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  • DOI: https://doi.org/10.1007/978-1-59745-443-8_10

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-756-3

  • Online ISBN: 978-1-59745-443-8

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