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Animal Cell Biotechnology pp 371–393Cite as

Configuration of Bioreactors

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Part of the book series: Methods in Biotechnology ((MIBT,volume 24))

Abstract

For basic research on animal cells and in process development and troubleshooting, lab-scale bioreactors (0.2–20 L) are used extensively. In this chapter setting up the bioreactor system for different configurations is described, and two special setups (acceleration stat and reactors in series) are treated. In addition, on-line measurement and control of bioreactor parameters is described, with special attention to controller settings (PID) and on-line measurement of oxygen consumption and carbon dioxide production. Finally, methods for determining the oxygen transfer coefficient are described.

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Author information

Authors and Affiliations

  1. Food and Bioprocess Engineering Group, Wageningen University, Wageningen, The Netherlands

    Dirk E. Martens & Evert Jan van den End

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  1. Dirk E. Martens
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  2. Evert Jan van den End
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Editors and Affiliations

  1. Institute for Bioprocess and Biochemical Engineering, Hamburg University of Technology, Hamburg, Germany

    Ralf Pörtner

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© 2007 Humana Press Inc., Totowa, NJ

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Martens, D.E., van den End, E.J. (2007). Configuration of Bioreactors. In: Pörtner, R. (eds) Animal Cell Biotechnology. Methods in Biotechnology, vol 24. Humana Press. https://doi.org/10.1007/978-1-59745-399-8_18

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  • DOI: https://doi.org/10.1007/978-1-59745-399-8_18

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-660-3

  • Online ISBN: 978-1-59745-399-8

  • eBook Packages: Springer Protocols

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