Abstract
Caveolin1, the main component of caveolae, plays a major role in regulating cell motility, gene expression, and cytoskeleton remodeling downstream of many membrane receptors. Here, we summarize different techniques set up to study changes in cell morphology and cell motility regulated by ERK/caveolin1 interactions during induction of epithelial mesenchymal transition (EMT) in mesothelial cells (MCs).
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Acknowledgements
This work was supported by grants from the MINECO (Spanish Ministry of Economy and Competitiveness) to M.A.D.P. (SAF2014-51876-R and CONSOLIDER CSD2009-00016) and from Fundació la Marató TV3 (674/C/2013) to M.A.D.P. The CNIC is supported by MINECO and the Pro-CNIC Foundation. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the chapter.
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Strippoli, R., Echarri, A., del Pozo, M.A. (2017). Cell-Based Assays to Study ERK Pathway/Caveolin1 Interactions. In: Jimenez, G. (eds) ERK Signaling. Methods in Molecular Biology, vol 1487. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6424-6_12
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DOI: https://doi.org/10.1007/978-1-4939-6424-6_12
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