Date: 12 Jun 2013

Dextran Sodium Sulfate-Induced Murine Inflammatory Colitis Model

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Abstract

Colitis is a chronic inflammatory disease of the colon that is characterized by recurring, acute episodes. Mouse models of colitis allow for the study of multiple aspects of this disease, including the innate immune response, epithelial and intestinal cell response, and wound healing. The following protocols cover acute, chronic, and cancer-associated colitis models.