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Considerations for Sequencing Analyses of Pancreatic Cancer Progression and Metastasis

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Pancreatic Cancer

Part of the book series: Methods in Molecular Biology ((MIMB,volume 980))

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Abstract

Sequencing analyses have been invaluable in identifying the genes associated with pancreatic ­carcinogenesis. However, whereas gene discovery related to carcinogenesis can be fairly straightforward, there are several additional aspects of experimental design that need to be considered when performing genetic analyses of metastatic disease. This chapter aims to review these issues and provide examples of the types of data generated.

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Author information

Authors and Affiliations

  1. Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, MD, USA

    Alvin Makohon-Moore & Christine A. Iacobuzio-Donahue

Authors
  1. Alvin Makohon-Moore
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  2. Christine A. Iacobuzio-Donahue
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Corresponding author

Correspondence to Christine A. Iacobuzio-Donahue .

Editor information

Editors and Affiliations

  1. , Irving Cancer Research Center, Columbia University, St. Nicholas Avenue 1130, New York, 10032, New York, USA

    Gloria H. Su

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Makohon-Moore, A., Iacobuzio-Donahue, C.A. (2013). Considerations for Sequencing Analyses of Pancreatic Cancer Progression and Metastasis. In: Su, G. (eds) Pancreatic Cancer. Methods in Molecular Biology, vol 980. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-287-2_6

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  • DOI: https://doi.org/10.1007/978-1-62703-287-2_6

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-286-5

  • Online ISBN: 978-1-62703-287-2

  • eBook Packages: Springer Protocols

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