Date: 22 Sep 2012

Phenotyping of Mouse Models with OCT

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Abstract

Optical coherence tomography (OCT) is an invaluable technique to perform noninvasive retinal imaging in small animal models such as mice. It provides virtual cross sections that correlate well with histomorphometric data with the advantage that multiple iterative measurements can be acquired in time line analyses to detect dynamic changes and reduce the amount of animals needed per study.