Protocol

Computational Biology

Volume 673 of the series Methods in Molecular Biology pp 223-230

Date:

Modeling Experimental Design for Proteomics

  • Jan ErikssonAffiliated withDepartment of Chemistry, Swedish University of Agricultural Sciences Email author 
  • , David FenyöAffiliated withThe Rockefeller University

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Abstract

The complexity of proteomes makes good experimental design essential for their successful investigation. Here, we describe how proteomics experiments can be modeled and how computer simulations of these models can be used to improve experimental designs.

Key words

Proteomics Mass spectrometry Experimental design Simulations Modeling