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Data Mining Techniques for the Life Sciences

Volume 609 of the series Methods in Molecular Biology pp 17-44

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Genomic Databases and Resources at the National Center for Biotechnology Information

  • Tatiana TatusovaAffiliated withNational Institute of Heath

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Abstract

The National Center for Biotechnology Information (NCBI), as a primary public repository of genomic sequence data, collects and maintains enormous amounts of heterogeneous data. Data for genomes, genes, gene expressions, gene variation, gene families, proteins, and protein domains are integrated with the analytical, search, and retrieval resources through the NCBI Web site. Entrez, a text-based search and retrieval system, provides a fast and easy way to navigate across diverse biological databases.

Customized genomic BLAST enables sequence similarity searches against a special collection of organism-specific sequence data and viewing the resulting alignments within a genomic context using NCBI’s genome browser, Map Viewer.

Comparative genome analysis tools lead to further understanding of evolutionary processes, quickening the pace of discovery.

Key words

bioinformatics genome metagenome database data management system sequence analysis