Volume 409 of the series Methods in Molecular Biology™ pp 61-74


The Immuno Polymorphism Database
  • James RobinsonAffiliated withAnthony Nolan Research Institute, Royal Free Hospital
  • , Steven G. E. MarshAffiliated withDepartment of Haematology, Anthony Nolan Research Institute, Royal Free Hospital

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The Immuno Polymorphism Database (IPD) (http://​www.​ebi.​ac.​uk/​ipd/​) is a set of specialist databases related to the study of polymorphic genes in the immune system. IPD currently consists of four databases: IPD-KIR, contains the allelic sequences of killer cell immunoglobulin-like receptors (KIRs); IPD-MHC, a database of sequences of the major histocompatibility complex (MHC) of different species; IPD-HPA, alloantigens expressed only on platelets; and IPD-ESTAB, which provides access to the European Searchable Tumour Cell Line Database, a cell bank of immunologically characterized melanoma cell lines. The IPD project works with specialist groups or nomenclature committees who provide and curate individual sections before they are submitted to IPD for online publication. The IPD project stores all the data in a set of related databases. Those sections with similar data, such as IPD-KIR and IPD-MHC, share the same database structure.

Key Words

KIR MHC nomenclature sequences alleles database