Protocol

Micro and Nano Technologies in Bioanalysis

Volume 544 of the series Methods in Molecular Biology™ pp 559-569

Date:

Magnetic Nanoparticles for Local Drug Delivery Using Magnetic Implants

  • Rodrigo Fernández-PachecoAffiliated withInstituto Universitario de Investigación en Nanociencia de Aragón (INA), Instituto de Ciencia de Materiales de Aragón (ICMA), Universidad de Zaragoza-CSIC
  • , J. Gabriel ValdiviaAffiliated withInstituto Universitario de Investigación en Nanociencia de Aragón (INA), Instituto de Ciencia de Materiales de Aragón (ICMA), Universidad de Zaragoza-CSIC
  • , M. Ricardo IbarraAffiliated withInstituto Universitario de Investigación en Nanociencia de Aragón (INA), Instituto de Ciencia de Materiales de Aragón (ICMA), Universidad de Zaragoza-CSIC

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Summary

This chapter is a brief description of the state of the art of the field of targeted drug delivery using magnetic implants. It describes the advantages and drawbacks of the use of internal magnets to concentrate magnetic nanoparticles near tumor locations, and the different approaches to this task performed in vitro and in vivo reviewed in literature are presented.

Key words

Magnetic Implants Magnetic nanoparticles Drug delivery