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Stem Cell Transcriptional Networks

Volume 1150 of the series Methods in Molecular Biology pp 153-160

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A Description of the Molecular Signatures Database (MSigDB) Web Site

  • Arthur LiberzonAffiliated withBroad Institute of MIT and Harvard, 301 Binney Street Email author 

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Abstract

Annotated lists of genes help researchers to prioritize their own lists of candidate genes and to plan follow-up studies. The Molecular Signatures Database (MSigDB) is one of the most widely used knowledge base repositories of annotated sets of genes involved in biochemical pathways, signaling cascades, expression profiles from research publications, and other biological concepts. Here we provide an overview of MSigDB and its online analytical tools.

Key words

Bioinformatics Database Genomics Molecular sequence annotation Gene expression profiling