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IMGT®, the International ImmunoGeneTics Information System® for Immunoinformatics

Methods for Querying IMGT® Databases, Tools, and Web Resources in the Context of Immunoinformatics

  • Protocol
Immunoinformatics

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 409))

Summary

IMGT ®, the international ImMunoGeneTics information system® (http://imgt.cines.fr), was created in 1989 by the Laboratoire d’ImmunoGénétique Moléculaire (LIGM) (Université Montpellier II and CNRS) at Montpellier, France, in order to standardize and manage the complexity of immunogenetics data. IMGT ® is recognized as the international reference in immunogenetics and immunoinformatics. IMGT ® is a high quality integrated knowledge resource, specialized in (i) the immunoglobulin (IG), T cell receptors (TR), major histocompatibility complex (MHC) of human and other vertebrates; (ii) proteins that belong to the immunoglobulin superfamily (IgSF) and to the MHC superfamily (MhcSF); and (iii) related proteins of the immune systems (RPI) of any species. IMGT ® provides a common access to standardized data from genome, proteome, genetics, and three-dimensional (3D) structures for the IG, TR, MHC, IgSF, MhcSF, and RPI. IMGT ® interactive on-line tools are provided for genome, sequence, and 3D structure analysis. IMGT ® Web resources comprise 8,000 HTML pages of synthesis and knowledge (IMGT Scientific chart, IMGT Repertoire, IMGT Education, etc.) and external links (IMGT Bloc-notes and IMGT other accesses).

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Acknowledgments

I thank Véronique Giudicelli, Patrice Duroux, Quentin Kaas, Joumana Jabado-Michaloud, Géraldine Folch, Chantal Ginestoux, Denys Chaume, and G ’erard Lefranc for helpful discussion. I am deeply grateful to the IMGT ® team for its expertise and constant motivation. IMGT ® is a registered mark of the Centre National de la Recherche Scientifique (CNRS). IMGT ® has received the National Bioinformatics Platform RIO label since 2001 (CNRS, INSERM, CEA, and INRA). IMGT ® was funded in part by the BIOMED1 (BIOCT930038), Biotechnology BIOTECH2 (BIO4CT960037) and 5th PCRDT Quality of Life and Management of Living Resources (QLG2-2000-01287) programmes of the European Union (EU). IMGT-ML was developed in collaboration with the EU Online Research Information Environment for the Life Sciences, ORIEL project (IST-2001-32688). IMGT® is currently supported by the CNRS, the Minist ‘ere de l'Education Nationale, de l’Enseignement Supérieur et de la Recherche (MENESR) (Université Montpellier II Plan Pluri-Formation, Institut Universitaire de France, ACI-IMPBIO IMP82-2004), the EU ImmunoGrid (IST-028069) programme, GIS AGENAE, R ’eseau National des G ’enopoles and the R ’egion Languedoc-Roussillon BIOSTIC-LR2004

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Authors and Affiliations

  1. Laboratoired’ImmunoGénétique Moléculaire, Institut Universitaire de France, Université Montpellier II, UPR CNRS 1142, Institut de Génétique Humaine, Montpellier Cedex, France

    Marie-Paule Lefranc

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  1. Marie-Paule Lefranc
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Editors and Affiliations

  1. The Jenner Institute, University of Oxford, Berkshire, UK

    Darren R. Flower

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© 2007 Humana Press Inc.

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Lefranc, MP. (2007). IMGT®, the International ImmunoGeneTics Information System® for Immunoinformatics. In: Flower, D.R. (eds) Immunoinformatics. Methods in Molecular Biology™, vol 409. Humana Press. https://doi.org/10.1007/978-1-60327-118-9_2

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  • DOI: https://doi.org/10.1007/978-1-60327-118-9_2

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-699-3

  • Online ISBN: 978-1-60327-118-9

  • eBook Packages: Springer Protocols

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