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Working with Ontologies

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Bioinformatics

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1525))

Abstract

Ontologies are powerful and popular tools to encode data in a structured format and manage knowledge. A large variety of existing ontologies offer users access to biomedical knowledge. This chapter contains a short theoretical background of ontologies and introduces two notable examples: The Gene Ontology and the ontology for Biological Pathways Exchange. For both ontologies a short overview and working bioinformatic applications, i.e., Gene Ontology enrichment analyses and pathway data visualization, are provided.

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Acknowledgements

This work was funded by the German ministry of education and research (BMBF) grants FKZ01ZX1508 and FKZ031L0024A.

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Authors and Affiliations

  1. Department of Medical Statistics, University Medical Center Göttingen, Humboldtallee 32, 37073, Göttingen, Germany

    Frank Kramer & Tim Beißbarth

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  1. Frank Kramer
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  2. Tim Beißbarth
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Correspondence to Frank Kramer .

Editor information

Editors and Affiliations

  1. Monash University, Melbourne, Victoria, Australia

    Jonathan M. Keith

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Kramer, F., Beißbarth, T. (2017). Working with Ontologies. In: Keith, J. (eds) Bioinformatics. Methods in Molecular Biology, vol 1525. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6622-6_6

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  • DOI: https://doi.org/10.1007/978-1-4939-6622-6_6

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-6620-2

  • Online ISBN: 978-1-4939-6622-6

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