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Acute Kidney Injury and Regenerative Medicine

  • Book
  • © 2020

Overview

Editors:
  1. Yoshio Terada

    1. Department of Endocrinology, Metabolism, and Nephrology, Kochi Medical School, Kochi University, Nankoku, Japan

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  2. Takashi Wada

    1. Department of Nephrology and Laboratory Medicine, Kanazawa University, Kanazawa, Japan

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  3. Kent Doi

    1. Department of Acute Medicine, The University of Tokyo, Tokyo, Japan

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  • Offers up-to-date information on the clinical-pathophysiological features of acute renal injury (AKI)

  • Presents new findings in AKI with plenty of experimental data

  • Covers regenerative medicine in the context of AKI and renal diseases

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Table of contents (26 chapters)

  1. Front Matter

    Pages i-ix
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  2. Diagnosis and Risk Factors of AKI

    1. Front Matter

      Pages 1-1
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    2. Acute Kidney Injury: Definition and Epidemiology

      • Taro Horino
      Pages 3-20

    3. Causes of AKI (Prerenal, Intrarenal, Postrenal)

      • Hiroki Ikai, Yoshiro Fujita
      Pages 21-32

    4. Pathophysiology of AKI

      • Hideo Yasuda
      Pages 33-45

    5. Diagnosis of AKI: Clinical Assessment, Novel Biomarkers, History, and Perspectives

      • Kiyoshi Mori, Noriko Mori
      Pages 47-58

    6. Risk Factors for AKI Development in Surgery (Non-cardiac Surgery)

      • Shu Wakino
      Pages 59-67

    7. Risk Factors for AKI Development in Acute Decompensated Heart Failure

      • Nobuhiko Joki, Yasushi Ohashi, Yuri Tanaka, Toshihide Hayashi, Ken Sakai, Hiroki Hase
      Pages 69-83

    8. Contrast-Induced Acute Kidney Injury

      • Yoshihide Fujigaki
      Pages 85-98

    9. Antibiotics- and Immunosuppressants-Related AKI

      • Kengo Furuichi, Keisuke Sako, Takashi Wada
      Pages 99-110

    10. AKI in Setting of Cancer

      • Yuichiro Kitai, Takeshi Matsubara, Motoko Yanagita
      Pages 111-124

    11. Community- and Hospital-Acquired Acute Kidney Injury

      • Sadudee Peerapornratana, Nattachai Srisawat
      Pages 125-144

  3. Complication of AKI

    1. Front Matter

      Pages 145-145
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    2. Complication of Homeostasis (Electrolytes and Acid-Base)

      • Atsuko Uehara, Yugo Shibagaki
      Pages 147-162

    3. Volume Overload and Pulmonary Complications

      • Masashi Tada, Hiroki Hayashi, Naotake Tsuboi, Yukio Yuzawa
      Pages 163-179

  4. Prevention and Management of AKI

    1. Front Matter

      Pages 181-181
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    2. Prophylaxis and Management of Acute Kidney Injury

      • Yasuhiro Komatsu
      Pages 183-200

    3. Postrenal AKI

      • Naoya Nagaya, Shigeo Horie
      Pages 201-213

    4. Acute Kidney Injury in Intensive Care Medicine

      • Kohei Yoshimoto, Kent Doi
      Pages 215-224

    5. Nondialytic Supportive Management of AKI

      • Hiroyuki Yamada
      Pages 225-237
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Keywords

About this book

This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis.
Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.


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Editors and Affiliations

  • Department of Endocrinology, Metabolism, and Nephrology, Kochi Medical School, Kochi University, Nankoku, Japan

    Yoshio Terada

  • Department of Nephrology and Laboratory Medicine, Kanazawa University, Kanazawa, Japan

    Takashi Wada

  • Department of Acute Medicine, The University of Tokyo, Tokyo, Japan

    Kent Doi

About the editors

Prof. Yoshio Terada
Department of Endocrinology, Metabolism and Nephrology, Kochi Medical School, Kochi University, Japan

Prof. Takashi Wada
Vice President,  Kanazawa University, Japan
Department of Nephrology and Laboratory Medicine, Kanazawa University, Japan

Dr. Kento Doi
Department of Acute Medicine, The University of Tokyo, Japan

Bibliographic Information

  • Book Title: Acute Kidney Injury and Regenerative Medicine

  • Editors: Yoshio Terada, Takashi Wada, Kent Doi

  • DOI: https://doi.org/10.1007/978-981-15-1108-0

  • Publisher: Springer Singapore

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Singapore Pte Ltd. 2020

  • Hardcover ISBN: 978-981-15-1107-3Published: 15 May 2020

  • Softcover ISBN: 978-981-15-1110-3Published: 16 May 2021

  • eBook ISBN: 978-981-15-1108-0Published: 14 May 2020

  • Edition Number: 1

  • Number of Pages: IX, 396

  • Number of Illustrations: 6 b/w illustrations, 33 illustrations in colour

  • Topics: Nephrology, Regenerative Medicine/Tissue Engineering

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