Overview
- Presents the latest findings on antimicrobial peptides
- Elucidates their mechanisms of antimicrobial action
- Examines AMP activities beyond antimicrobial action
- Discusses the progress made, and obstacles to, their clinical application
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1117)
Access this book
Tax calculation will be finalised at checkout
Other ways to access
Table of contents (15 chapters)
-
Front Matter
-
Introduction
-
Front Matter
-
-
Mechanisms of Antimicrobial Action
-
Front Matter
-
-
Other Activities of AMPs
-
Front Matter
-
-
Towards Clinical Applications
-
Front Matter
-
Keywords
About this book
This book presents an overview of antimicrobial peptides (AMPs), their mechanisms of antimicrobial action, other activities, and various problems that must still be overcome regarding their clinical application. Divided into four major parts, the book begins with a general overview of AMPs (Part I), and subsequently discusses the various mechanisms of antimicrobial action and methods for researching them (Part 2). It then addresses a range of activities other than antimicrobial action, such as cell penetration, antisepsis, anticancer, and immunomodulatory activities (Part 3), and explores the prospects of clinical application from various standpoints such as the selective toxicity, design, and discovery of AMPs (Part 4). A huge number of AMPs have been discovered in plants, insects, and vertebrates including humans, and constitute host defense systems against invading pathogenic microorganisms. Consequently, many attempts have been made to utilize AMPs as antibiotics. AMPs could help to solve the urgent problem of drug-resistant bacteria, and are also promising with regard to sepsis and cancer therapy. Gathering a wealth of information, this book will be a bible for all those seeking to develop antibiotics, anti-sepsis, or anticancer agents based on AMPs.
Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Antimicrobial Peptides
Book Subtitle: Basics for Clinical Application
Editors: Katsumi Matsuzaki
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-981-13-3588-4
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2019
Hardcover ISBN: 978-981-13-3587-7Published: 29 April 2019
eBook ISBN: 978-981-13-3588-4Published: 12 April 2019
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: VIII, 304
Number of Illustrations: 18 b/w illustrations, 55 illustrations in colour
Topics: Pharmacology/Toxicology, Biological and Medical Physics, Biophysics, Biochemistry, general, Cancer Research