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Telomere Territory and Cancer

  • Book
  • © 2013

Overview

Editors:
  1. Parvin Mehdipour

    1. School Of Medicine, Tehran University of Medical Sciences, Department of Medical Genetics, Tehran, Iran

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  • Is architected on the basis of our original research data and images
  • Developmental manner of chapters
  • Flavour of both basic and clinical approaches
  • Hopeful perspective for biomarker and targeted therapy
  • Supports the insight of personalized cancer medicine for future
  • Includes supplementary material: sn.pub/extras

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Table of contents (8 chapters)

  1. Front Matter

    Pages 1-1
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  2. Telomerase: from Aging to Human Cancers

    • N. Parsa
    Pages 1-28

  3. Telomerase: Basic and Clinical Approaches

    • S. Saied Hosseini-Asl
    Pages 29-39

  4. Detection of Telomerase Activity: A New Strategy for Detecting Low Activity of Telomerase

    • S. Saied Hosseini-Asl, P. Mehdipour
    Pages 41-53

  5. Telomere, Regulation and Tumorigenesis

    • M. Kheirollahi
    Pages 55-98

  6. Novel Hypothesis on Telomere Length: Heterogenic Targets as Genomic/Somatic Diverse Value in Breast Cancer and Brain Tumor

    • P. Mehdipour
    Pages 99-141

  7. Telomere Length, Methylation and Nutrition

    • F. Karami, P. Mehdipour
    Pages 143-161

  8. Cancer Stem Cells

    • P. Mehdipour, N. Parsa
    Pages 163-188

  9. Closing Highlights: Final Statements at a Glance

    • P. Mehdipour
    Pages 189-198

  10. Back Matter

    Pages 196-196
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Keywords

About this book

Timing, racing, combating, struggling and targeting are some actions through which cellular fate could be reflected and evaluated. Interaction between cell territory and environment occur during pre-embryonic, fetal development, and post-natal periods. What the researchers observe as the outcome of telomeres behavior is only the peak of an ice mountain within a stormy ocean. Cellular life depends on programmed behavior of telomeres, capable to surprise the cells. Telomeres provide an introduction to the history of our cells which govern the quality of life and status of health. Telomeres as the cooperative territory are capable of stabilizing the chromosomal territory. The status of telomeres reflects the key information, announcing the real age of individuals, and may be a valuable marker for prognosis and predicting cancer. Telomere territory is characterized with a multi-disciplinary manner. Therefore, this book is aimed to offer a wide range of chapters, hoping to be useful for diverse audiences, including hematologists-oncologists, radiotherapists, surgeons, cancer researchers, and all the sectors who affect the macro- and micro- environmental domains. Finally, telomeres are sensitive, cooperative, and trustable targets. It is worth to state that ‘telomeres are messengers of NATURE’, let’s to know them as they are.

Editors and Affiliations

  • School Of Medicine, Tehran University of Medical Sciences, Department of Medical Genetics, Tehran, Iran

    Parvin Mehdipour

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