Overview
- Editors:
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Pier Andrea Borea
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Ist. Farmacologia, Universita Ferrara, Ferrara, Italy
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Table of contents (16 chapters)
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Physico-chemical Properties and Molecular Biology
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- Pier Andrea Borea, Stefania Gessi, Stefania Merighi, Katia Varani
Pages 29-48
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Signal Transduction
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- Stefania Merighi, Carolina Simioni, Rob Lane, Adriaan P. Ijzerman
Pages 61-73
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- Maria Letizia Trincavelli, Osele Ciampi, Claudia Martini
Pages 75-90
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Medicinal Chemistry
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- Kenneth A. Jacobson, Zhan-Guo Gao, Dilip K. Tosh, Gangadhar J. Sanjayan, Sonia de Castro
Pages 93-120
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- Pier Giovanni Baraldi, Romeo Romagnoli, Giulia Saponaro, Stefania Baraldi, Mojgan Aghazadeh Tabrizi, Delia Preti
Pages 121-147
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- Stefano Moro, Erika Morizzo, Kenneth A. Jacobson
Pages 149-161
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Effects on Tissues and Organs and Therapeutic Applications
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Front Matter
Pages 164-164
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- Felicita Pedata, Anna Maria Pugliese, Ana M. Sebastião, Joaquim A. Ribeiro
Pages 165-188
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- John P. Headrick, Jason N. Peart, Tina C. Wan, Wai-Meng Kwok, John A. Auchampach
Pages 189-208
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- Stefania Gessi, Valerio Sacchetto, Eleonora Fogli, John Fozard
Pages 235-256
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- Bruce T. Liang, Maria Urso, Edward Zambraski, Kenneth A. Jacobson
Pages 257-280
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- Stefania Gessi, Stephen MacLennan, Edward Leung, Pier Andrea Borea
Pages 281-288
About this book
This book, with its 16 chapters, documents the present state of knowledge of the adenosine A receptor. It covers a wide range of information, including data from 3 studies of theoretical, molecular and cellular pharmacology, signal transduction, integrative physiology, new drug discoveries and clinical applications. It fills an important gap in the literature since no alternative source of such information is currently available. Although the A receptor is increasingly being recognized for 3 its increasing number of biological roles throughout the body and many A receptor 3 ligands have proven useful in elucidating peripheral and central pathologies, many issues remain unresolved. Moreover, research activity in this field continues to grow exponentially, resulting in a constant flow of new information. The chapters in this book cover both basic science and the relevant applications and provide an authoritative account of the current status of the field. They have enabled my goal as editor to make “A Adenosine Receptors from Cell Biology to Pharmacology and 3 Therapeutics” an up to date, scientifically excellent, reference source, attractive to basic and clinical scientists alike, a reality. Detailed understanding of the physico-chemical aspects and molecular biology of the A receptor provides a solid basis for its future development as a target for 3 adenosine-based pharmacotherapies (Chapters 2 and 3).
Editors and Affiliations
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Ist. Farmacologia, Universita Ferrara, Ferrara, Italy
Pier Andrea Borea
