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  • Book
  • © 2011

Pediatric Clinical Pharmacology

Editors:

  1. Hannsjörg W. Seyberth

    1. Klinik für Kinder- und Jugendmedizin, Univ.Klinikum Marburg, Marburg, Germany

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  2. Anders Rane

    1. Karolinska Institutet, Dept. Laboratory Medicine, Karolinska University Hostpital, Stockholm, Sweden

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  3. Matthias Schwab

    1. für Klinische Pharmakologie (IKP), Dr. Margarete Fischer-Bosch Institut, Stuttgart, Germany

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  • Written by international leading experts in the field
  • With numerous illustrations
  • Describes the present state of pediatric pharmacology and gives an overview on this fascinating field of research to colleagues from other disciplines
  • Includes supplementary material: sn.pub/extras

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 205)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xii
    PDF

  2. General Considerations and Methodological Aspects

    1. Front Matter

      Pages 1-1
      PDF

  3. General Considerations and methodological aspects

    1. Basics and Dynamics of Neonatal and Pediatric Pharmacology

      • Hannsjörg W. Seyberth, Ralph E. Kauffman
      Pages 3-49

    2. Developmental Pharmacokinetics

      • Johannes N. van den Anker, Matthias Schwab, Gregory L. Kearns
      Pages 51-75

    3. Principles of Therapeutic Drug Monitoring

      • Wei Zhao, Evelyne Jacqz-Aigrain
      Pages 77-90

    4. Drug Delivery and Formulations

      • Jörg Breitkreutz, Joachim Boos
      Pages 91-107

  4. Development of Pediatric Medicines

    1. Front Matter

      Pages 109-109
      PDF

  5. Development of pediatric medicines

    1. Development of Paediatric Medicines: Concepts and Principles

      • Klaus Rose, Oscar Della Pasqua
      Pages 111-124

    2. Study Design and Simulation Approach

      • Stephanie Läer, Bernd Meibohm
      Pages 125-148

    3. Efficacy Assessment in Paediatric Studies

      • Siri Wang, Pirjo Laitinen-Parkkonen
      Pages 149-168

    4. Safety Assessment in Pediatric Studies

      • Gideon Koren, Abdelbasset Elzagallaai, Fatma Etwel
      Pages 169-180

    5. Small Sample Approach, and Statistical and Epidemiological Aspects

      • Martin Offringa, Hanneke van der Lee
      Pages 181-202

    6. Sample Collection, Biobanking, and Analysis

      • Maurice J. Ahsman, Dick Tibboel, Ron A. A. Mathot, Saskia N. de Wildt
      Pages 203-217

    7. Ethical Considerations in Conducting Pediatric Research

      • Michelle Roth-Cline, Jason Gerson, Patricia Bright, Catherine S. Lee, Robert M. Nelson
      Pages 219-244

    8. Pediatric Regulatory Initiatives

      • Steven Hirschfeld, Agnes Saint-Raymond
      Pages 245-268

  6. Specific Pediatric Pharmacology

    1. Front Matter

      Pages 269-269
      PDF

  7. Specific pediatric pharmacology

    1. Fetal Medicine and Treatment

      • Magnus Westgren
      Pages 271-283

    4. Preventive Medicines

      • Ulrich Heininger
      Pages 317-337
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About this book

The objective of this volume is to give an overview of the present state of the art of pediatric clinical pharmacology including developmental physiology, pediatric-specific pathology, special tools and methods for development of drugs for children (assessment of efficacy, toxicity, long-term safety etc.) as well as regulatory and ethical knowledge and skills. In the future, structural and educational changes have to lead back to a closer cooperation and interaction of pediatrics with (clinical) pharmacology and pharmacy.
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Keywords

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Editors and Affiliations

  • Klinik für Kinder- und Jugendmedizin, Univ.Klinikum Marburg, Marburg, Germany

    Hannsjörg W. Seyberth

  • Karolinska Institutet, Dept. Laboratory Medicine, Karolinska University Hostpital, Stockholm, Sweden

    Anders Rane

  • für Klinische Pharmakologie (IKP), Dr. Margarete Fischer-Bosch Institut, Stuttgart, Germany

    Matthias Schwab

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Bibliographic Information

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Policies and ethics

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Access via your institution

Buy it now

eBook USD 389.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 499.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 499.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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