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Post-Transplant Lymphoproliferative Disorders

  • Book
  • © 2010

Overview

  • Explores in detail every aspect of post-transplant lymphoproliferative disorders, which can be expected to develop in 5-10% of transplant recipients

  • Discusses the role of Epstein-Barr virus, documents clinical and pathological features, and assesses treatment options

  • Designed to aid the different professionals who care for patients with post-transplant lymphoproliferative disorders, whether beginners or experts

  • Includes supplementary material: sn.pub/extras

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Table of contents (15 chapters)

Keywords

About this book

Post-transplant lymphoproliferative disorders are a group of conditions that straddle the borders between infection and malignancy. They were very rare prior to the mid-1980s but now can be expected to develop in 1-10% of transplant recipients. While some cases are reversible with reduction in immunosuppression, more severe forms are indistinguishable from frank lymphomas.

This book sets out to cover in depth every aspect of these disorders, including both basic science and clinical topics. The epidemiology is reviewed, and careful attention is paid to the role of Epstein-Barr virus in their development. Clinical features are documented and clear guidance is provided on diagnosis, with thorough description of pathologic and imaging findings. Further chapters are devoted to treatment, prognosis, preventive and pre-emptive strategies, and organ-specific considerations.

The state-of-the-art information contained in this book will aid researchers as well as the many different professionals involved in caring for patients with post-transplant lymphoproliferative disorders. The comprehensive and detailed coverage will appeal to those who already have some expertise in the field, yet the book will also serve as an invaluable resource for beginners in transplantation.

Reviews

From the reviews: “The authors present a comprehensive overview of the presentation, diagnosis, and management of post-transplant lymphoproliferative disorders (PTLD) and post-transplant Epstein-Barr virus (EBV) infection. … This work will prove useful to all physicians who care for transplant recipients. … It will certainly prove a useful contribution.” (Truman M. Earl, Doody’s Review Service, March, 2010)

Editors and Affiliations

  • Pediatric Kidney Transplantation, Shands Hospital at UF, University of Florida College of Medicine Medical Director, Gainesville, USA

    Vikas R. Dharnidharka

  • Division of Infectious Diseases Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, USA

    Michael Green

  • Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, USA

    Steven A. Webber

Bibliographic Information

  • Book Title: Post-Transplant Lymphoproliferative Disorders

  • Editors: Vikas R. Dharnidharka, Michael Green, Steven A. Webber

  • DOI: https://doi.org/10.1007/978-3-642-01653-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2010

  • Softcover ISBN: 978-3-642-42285-0Published: 13 December 2014

  • eBook ISBN: 978-3-642-01653-0Published: 01 March 2010

  • Edition Number: 1

  • Number of Pages: XII, 190

  • Topics: Nephrology, Transplant Surgery, Oncology, General Surgery, Cardiac Surgery, Infectious Diseases

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