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Toll-Like Receptors (TLRs) and Innate Immunity

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 183)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-xi
  2. Toll-Like Receptors (TLRs) and Their Ligands

    • Satoshi Uematsu, Shizuo Akira
    Pages 1-20
  3. Signalling of Toll-Like Receptors

    • Constantinos Brikos, Luke A. J. O’Neill
    Pages 21-50
  4. TLR9-Mediated Recognition of DNA

    • Thomas Müller, Svetlana Hamm, Stefan Bauer
    Pages 51-70
  5. RNA Recognition via TLR7 and TLR8

    • Veit Hornung, Winfried Barchet, Martin Schlee, Gunther Hartmann
    Pages 71-86
  6. Fungal Recognition by TLR2 and Dectin-1

    • Helen S. Goodridge, David M. Underhill
    Pages 87-109
  7. Heat Shock Proteins and Toll-Like Receptors

    • Alexzander Asea
    Pages 111-127
  8. Dendritic Cell Subsets and Toll-Like Receptors

    • Hubertus Hochrein, Meredith O’Keeffe
    Pages 153-179
  9. Structure of Toll-Like Receptors

    • Nicholas J. Gay, Monique Gangloff
    Pages 181-200
  10. Vaccination with Messenger RNA (mRNA)

    • Steve Pascolo
    Pages 221-235
  11. Back Matter

    Pages 237-240

About this book

Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.

Editors and Affiliations

  • Institut für Immunologie BMFZ, Philipps-Universität Marburg, Marburg, Germany

    Stefan Bauer

  • Abteilung für Klinische Pharmakologie, Universitätsklinikum Bonn, Bonn, Germany

    Gunther Hartmann

Bibliographic Information

  • Book Title: Toll-Like Receptors (TLRs) and Innate Immunity

  • Editors: Stefan Bauer, Gunther Hartmann

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-540-72167-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2008

  • Hardcover ISBN: 978-3-540-72166-6Published: 18 December 2007

  • Softcover ISBN: 978-3-642-09133-9Published: 30 November 2010

  • eBook ISBN: 978-3-540-72167-3Published: 11 December 2007

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: XII, 240

  • Number of Illustrations: 21 b/w illustrations, 4 illustrations in colour

  • Topics: Pharmacology/Toxicology, Immunology, Medical Microbiology

Buy it now

Buying options

eBook USD 259.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 329.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access