Editors:
- Includes supplementary material: sn.pub/extras
Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 167)
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Table of contents (16 chapters)
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Front Matter
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General Aspects of PKs Inhibition
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Pharmacological Potential and Inhibitors of Individual Classes of Protein Kinases
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Pharmacological Potential and Inhibitors of Individual Classes of Protein Phosphatases
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Inhibitors in Clinical Use or Advanced Clinical Trials
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Back Matter
About this book
The aims of this volume are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal is attained by contributions of leader investigators in the field, who address the issue from different angles.
Editors and Affiliations
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Dipartimento di Chimica Biologica, Università di Padova, Padova, Italy
Lorenzo A. Pinna
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MRC Protein Phosphorylation Unit, School of Life Sciences, University of Dundee, Dundee, Scotland, UK
Patricia T.W. Cohen
About the editors
The Editor (L.A. Pinna) is full Professor of Medical Chemistry at the University of Padova since 1975. He has been involved for over 30 years in the study of various aspects of protein phosphorylation, with special reference to the analysis of consensus sequences of protein kinases and the development of peptide substrates for the specific monitoring of individual members of this family of enzymes. In this field he has published more than 290 original pepers and a number of review articles in international journals. Over the last years he has provided major contributions to the molecular and structural enzymology of protein kinases implicated in cell fate decision and in the development of inhibitors of one of these enzymes.
The co-Editor (P.T.W. Cohen) is an authority in the field of protein phosphatases.
Bibliographic Information
Book Title: Inhibitors of Protein Kinases and Protein Phosphates
Editors: Lorenzo A. Pinna, Patricia T.W. Cohen
Series Title: Handbook of Experimental Pharmacology
DOI: https://doi.org/10.1007/b137900
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Berlin Heidelberg 2005
Hardcover ISBN: 978-3-540-21242-3Published: 04 October 2004
Softcover ISBN: 978-3-642-42206-5Published: 28 November 2014
eBook ISBN: 978-3-540-26670-9Published: 30 March 2006
Series ISSN: 0171-2004
Series E-ISSN: 1865-0325
Edition Number: 1
Number of Pages: X, 458
Topics: Pharmacology/Toxicology, Oncology, Pathology, Medical Biochemistry