Edge-to-Edge Mitral Repair

1. Front Matter

   Pages i-viii

   PDF

2. The Genesis of the Edge-to-Edge Technique

   • Ottavio Alfieri

   Pages 1-6

3. The Principle: From a Computational Model to Clinical Validation

   • Francesco Sturla, Emiliano Votta, Maurizio Taramasso, Andrea Guidotti, Alberto Redaelli, Francesco Maisano

   Pages 7-18

4. Technical Aspects: Sternotomy and Minimally Invasive Approaches

   • Andrea Fumero, Michele De Bonis

   Pages 19-29

5. Is There a Role for the Edge-to-Edge Technique in Robotic Valve Mitral Repair?

   • W. Randolph Chitwood Jr.

   Pages 31-42

6. Echocardiographic Assessment of a Double-Orifice Mitral Valve: Tips and Tricks

   • Giovanna Di Giannuario, Emanuela Alati, Giovanni La Canna

   Pages 43-64

7. The Early Phase of Clinical Application: Lessons Learned

   • Roberto Lorusso, Enrico Vizzardi, Sandro Gelsomino

   Pages 65-73

8. Results of the Edge-to-Edge Mitral Valve Repair

   • Michele De Bonis, Elisabetta Lapenna, Gabriele Del Castillo, Ottavio Alfieri

   Pages 75-91

9. Edge-to-Edge Technique for Mitral Regurgitation Associated with Hypertrophic Cardiomyopathy

   • Jean-François Obadia

   Pages 93-97

10. Mitral Stenosis After Edge-to-Edge Repair: Is It an Issue?

    • Giovanna Di Giannuario, Giovanni La Canna

    Pages 99-109

11. Surgical Indications and Contraindications of the Edge-to-Edge

    • Alberto Pozzoli

    Pages 111-120

12. The Case of Surgical Edge-to-Edge Repair Without Annuloplasty: Now We Know

    • Elisabetta Lapenna, Davide Schiavi, Gabriele Del Castillo, Michele De Bonis

    Pages 121-128

13. Evolution of the Edge-to-Edge Repair: From a Surgical to a Percutaneous Approach

    • Stefano Benussi, Alberto Pozzoli, Maurizio Taramasso, Paolo Denti

    Pages 129-135

14. State of the Art of the MitraClip Therapy: Who, When, and How?

    • Paolo Denti, Nicola Buzzatti, Giovanni La Canna

    Pages 137-146

15. Clinical Results of the Percutaneous Edge-to-Edge Repair: Lights and Shadows

    • Maurizio Taramasso, Alberto Pozzoli, Antonio Colombo

    Pages 147-156

16. Future Perspectives of the Edge-to-Edge Repair

    • Paolo Denti, Nicola Buzzatti, Francesco Maisano

    Pages 157-164

17. Conclusions

    • Ottavio Alfieri

    Pages 165-166

This is the first comprehensive review of the edge-to-edge technique for mitral repair, which was introduced into the surgical armamentarium in 1991 by one of the authors, Ottavio Alfieri. The surgical technique employed in edge-to-edge repair today provides the basis for the only reliable method of percutaneous correction of degenerative mitral regurgitation. The book traces the evolution of the edge-to-edge technique from a surgical to a percutaneous approach, documenting indications, contraindications, technical aspects, controversies and clinical outcomes. Detailed attention is devoted to the MitraClip procedure, which reproduces the Alfieri stitch percutaneously and has to date been used in more than 20,000 patients worldwide. The state of the art in MitraClip therapy is described, with clear explanation of when and how to use the MitraClip system. The reader will learn all aspects of percutaneous edge-to-edge repair, which is recommended for use in carefully selected patients in the new ESC/EACTS guidelines for the management of valvular heart disease and in the ESC guidelines on heart failure. The group at San Raffaele Hospital, Milan, has accumulated by far the largest experience in the world with the technique and over the years has been very active in its promotion and scientific evaluation. This book reflects that depth of knowledge and will be of great interest to cardiac surgeons and interventional and clinical cardiologists.  

• MitraClip
• Mitral regurgitation
• Mitral stenosis
• Mitral valve
• Percutaneous mitral repair
• Ultrasonography

• Department of Cardiac Surgery, San Raffaele Hospital, Milan, Italy

  Ottavio Alfieri, Michele De Bonis, Giovanni La Canna

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