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  • Book
  • © 2015

Genomics, Personalized Medicine and Oral Disease

Editors:

  1. Stephen T. Sonis, DMD, DMSc

    1. Brigham and Women’s Hospital, Boston, USA

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  • This book catalyzes the application of genomics to oral diseases by comprehensively presenting focused discussions on the current state of knowledge

  • Also focuses on gene-based therapies and pharmacogenomics application to oral diseases

  • Written by leaders in the field

  • Includes supplementary material: sn.pub/extras

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xiv
    PDF

  2. Fundamentals of Genetics and Genomics

    • Stephen T. Sonis
    Pages 1-10

  3. Current and Evolving Technologies

    • J. Robert Chang, Enkhtsetseg Purev, Winston Patrick Kuo
    Pages 11-34

  4. The Oral Microbiome and Its Relationship to Genomics and Oral Disease

    • Ingrid Glurich, Sanjay Shukla, Amit Acharya, Geoffrey S. Ginsburg, Murray H. Brilliant
    Pages 35-65

  5. Host Genomics and Response to Infectious Agents

    • Manuela Moraru, Carlos Vilches
    Pages 67-90

  6. Developmental Anomalies – Clefts

    • Elizabeth J. Leslie, Mary L. Marazita
    Pages 91-116

  7. Caries

    • John R. Shaffer, Mary L. Marazita
    Pages 117-144

  8. Periodontal Disease

    • Arne S. Schäfer
    Pages 145-166

  9. Aphthous Stomatitis

    • Ricardo Carneiro Borra, Priscila Maria de Andrade
    Pages 167-183

  10. Lichen Planus

    • Nicola Luigi Bragazzi, Claudio Nicolini
    Pages 185-217

  11. Blistering Diseases – Pemphigoid

    • Raman Mehrzad, Shawn Shetty, A. Razzaque Ahmed
    Pages 219-251

  12. Salivary Gland Diseases

    • Astrid Rasmussen, Christopher J. Lessard, Kathy L. Sivils
    Pages 253-272

  13. Premalignant Lesions

    • Chia-Cheng Li, Zhe Li, Reshma S Menon, Sook-Bin Woo
    Pages 273-292

  14. Oral Cancer

    • Srinivas Vinod Saladi, Leif W. Ellisen
    Pages 293-309

  15. Bisphosphonate Related Osteonecrosis of the Jaw

    • Athanasios Zavras
    Pages 311-331

  16. Gene Therapy for Xerostomia

    • Bruce J. Baum
    Pages 333-343

  17. Gene Therapy for Mucositis

    • Joel S. Greenberger, Michael W. Epperly, Peter Wipf, Song Li, Valerian Kagan, Xiang Gao
    Pages 345-362

  18. Pharmacogenomics for Oral Disease

    • Kenneth S. Kornman, Gordon W. Duff, Kenneth Huttner, Peter J. Polverini, Jan Ching Chun Hu
    Pages 363-388

  20. Back Matter

    Pages 405-408
    PDF
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About this book

The objective of this book is to catalyze the application of genomics to the diagnosis and treatment of oral diseases by comprehensively presenting focused discussions on the current state of knowledge. The first section book provides basic information about genetics, genomics and personalized medicine and the informatical methods available to apply and organize genetic data so that it has clinical relevance. Recognizing the genetic robustness of the oral cavity, the introductory section includes chapters on the oral micro biome and host genomics and response to infectious agents. The next two sections contain chapters which describe the genomics of specific oral diseases and conditions, including the genetic basis for mechanism and risk of treatment toxicities associated with cancer therapy and bisphosphonates. Four chapters focus on gene-based therapies and the pharmacogenomics applied to oral disease. The final chapter presents a provocative summary which describes a comprehensive vision of the melding of genomics to personalized medicine and the potential actionable outcomes that will likely affect clinical practice in the upcoming years.
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Keywords

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Editors and Affiliations

  • Brigham and Women’s Hospital, Boston, USA

    Stephen T. Sonis, DMD, DMSc

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Bibliographic Information

  • Book Title: Genomics, Personalized Medicine and Oral Disease

  • Editors: Stephen T. Sonis, DMD, DMSc

  • DOI: https://doi.org/10.1007/978-3-319-17942-1

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-17941-4Published: 30 September 2015

  • Softcover ISBN: 978-3-319-34737-0Published: 29 October 2016

  • eBook ISBN: 978-3-319-17942-1Published: 17 September 2015

  • Edition Number: 1

  • Number of Pages: XIV, 408

  • Number of Illustrations: 11 b/w illustrations, 36 illustrations in colour

  • Topics: Human Genetics, Bioinformatics

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Buy it now

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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