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  • © 2015

An Information Technology Framework for Predictive, Preventive and Personalised Medicine

A Use-Case with Hepatocellular Carcinoma

  • Provides a roadmap for integrating Information Technology with PPPM
  • Proposes a methodology for managing vast amounts of personal medical data for decision support by means of Bayesian networks
  • Introduces new concepts such as a Digital Patient Model and Model Guided Therapy
  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Predictive, Preventive and Personalised Medicine (APPPM, volume 8)

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Softcover Book USD 109.99
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  • Dispatched in 3 to 5 business days
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Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xx
  2. Introduction

    • Leonard Berliner, Heinz U. Lemke
    Pages 1-7
  3. The Digital Patient Model and Model Guided Therapy

    • Leonard Berliner, Heinz U. Lemke
    Pages 9-19
  4. Hepatocellular Carcinoma and Patient Assessment

    • Smruti Mohanty, Sid Verma, David Dosik, Hesham Hazin, Leonard Berliner
    Pages 21-32
  5. Imaging in Hepatocellular Carcinoma: Radiologic Assessment

    • Irene Bargellini, Valentina Battaglia, Davide Caramella, Carlo Bartolozzi
    Pages 33-44
  6. Imaging in Hepatocellular Carcinoma: PET/CT

    • Giuseppe Esposito
    Pages 45-51
  7. Personalized Chemotherapy for Hepatocellular Carcinoma

    • Hesham Hazin, David Dosik
    Pages 53-60
  8. Surgical Treatment for Hepatocellular Carcinoma

    • Smruti Mohanty, Leonard Berliner, Syed Shah
    Pages 61-68
  9. Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Therapies

    • Eric van Sonnenberg, Leonard Berliner
    Pages 77-83
  10. Radiation Oncology in the Treatment of Hepatocellular Carcinoma

    • Hani Ashamalla, Malcolm D. Mattes
    Pages 93-102
  11. Design of an IT System for Hepatocellular Carcinoma

    • Leonard Berliner, Heinz U. Lemke
    Pages 103-117
  12. Outlook and Expert Recommendations for Predictive, Preventive and Personalized Medicine and Hepatocellular Carcinoma

    • Leonard Berliner, Heinz U. Lemke, Hani Ashamalla, Smruti Mohanty
    Pages 119-127
  13. Back Matter

    Pages 129-130

About this book

This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes.

Editors and Affiliations

  • Weill Cornell Medical College of Cornell, New York, USA

    Leonard Berliner

  • Technical University of Berlin, Kuessaberg, Germany

    Heinz U. Lemke

Bibliographic Information

  • Book Title: An Information Technology Framework for Predictive, Preventive and Personalised Medicine

  • Book Subtitle: A Use-Case with Hepatocellular Carcinoma

  • Editors: Leonard Berliner, Heinz U. Lemke

  • Series Title: Advances in Predictive, Preventive and Personalised Medicine

  • DOI: https://doi.org/10.1007/978-3-319-12166-6

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-12165-9Published: 12 June 2015

  • Softcover ISBN: 978-3-319-38434-4Published: 17 October 2016

  • eBook ISBN: 978-3-319-12166-6Published: 04 March 2015

  • Series ISSN: 2211-3495

  • Series E-ISSN: 2211-3509

  • Edition Number: 1

  • Number of Pages: XX, 130

  • Number of Illustrations: 8 b/w illustrations, 15 illustrations in colour

  • Topics: Health Informatics, Data Mining and Knowledge Discovery, Oncology, Hepatology, Simulation and Modeling

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access