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  • Book
  • © 2014

Recent Developments in the Regulation of Kinins

  • Presents recent developments in the regulation of kinins
  • Focuses on the role of the kallikrein-kinin system in various diseases
  • Antagonists/agonists of bradykinin, an important mediator involved in inflammatory conditions, are discussed
  • Includes supplementary material: sn.pub/extras

Part of the book series: Progress in Drug Research (PDR, volume 69)

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Table of contents (6 chapters)

  1. Front Matter

    Pages i-ix
  2. The Kallikrein–Kinin Pathways in Hypertension and Diabetes

    • Jagdish N. Sharma, Parvathy Narayanan
    Pages 15-36
  3. Tissue Kallikrein-Kinin Therapy in Hypertension and Organ Damage

    • Julie Chao, Grant Bledsoe, Lee Chao
    Pages 37-57
  4. The Kallikrein-Kinin System in Diabetic Retinopathy

    • Menakshi Bhat, Mylène Pouliot, Réjean Couture, Elvire Vaucher
    Pages 111-143
  5. Genetic Manipulation and Genetic Variation of the Kallikrein-Kinin System: Impact on Cardiovascular and Renal Diseases

    • Jean-Pierre Girolami, Nelly Blaes, Nadine Bouby, François Alhenc-Gelas
    Pages 145-196
  6. Back Matter

    Pages 197-198

About this book

This volume presents key topics of current interest with regard to several pathophysiological conditions including (a) the basic and clinical aspects of bradykinin receptor antagonists, (b) the kallikrein-kinin pathways in hypertension and diabetes, (c) tissue kallikrein-kinin therapy for hypertension and organ damage, (d) the renal (tissue) kallikrein-kinin system in the kidney and novel potential drugs for salt-sensitive hypertension, (e) the kallikrein-kinin system in diabetes retinopathy, and (f) genetic manipulation and genetic variation of the kallikrein-kinin system and their impacts on cardiovascular and renal disease. Written by internationally reputed scientists, the book provides an essential overview of the latest developments in the field of kinin research, making it a valuable asset for endocrinologists, nephrologists, cardiologists, pharmacologists, physiologists, ophthalmologists and rheumatologists. Furthermore, it is also intended for postgraduate students in the fields of medicine, pharmacy, physiology and pharmacology, and those working at research organizations.

Editors and Affiliations

  • Health Sciences Center, Faculty of Pharmacy, Department of Pharmacology and Therapeutics, Kuwait University, Safat, Kuwait

    Jagdish N. Sharma

Bibliographic Information

  • Book Title: Recent Developments in the Regulation of Kinins

  • Editors: Jagdish N. Sharma

  • Series Title: Progress in Drug Research

  • DOI: https://doi.org/10.1007/978-3-319-06683-7

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2014

  • Hardcover ISBN: 978-3-319-06682-0Published: 17 June 2014

  • Softcover ISBN: 978-3-319-34582-6Published: 23 August 2016

  • eBook ISBN: 978-3-319-06683-7Published: 26 May 2014

  • Series ISSN: 0071-786X

  • Series E-ISSN: 2297-4555

  • Edition Number: 1

  • Number of Pages: IX, 198

  • Number of Illustrations: 10 b/w illustrations, 7 illustrations in colour

  • Topics: Pharmacology/Toxicology, Human Physiology, Endocrinology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access