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Using R for Biostatistics

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  • © 2021

Overview

  • Includes step-by-step processes on the use of R for data organization using multiple data formats: comma-separated values, Internet-hosted spreadsheets, tab-separated values, white space
  • Gives attention to both parametric and nonparametric issues when selecting R functions for statistical analysis
  • Provides numerous examples of how the ggplot2 package is used to make beautiful graphics for biostatistics
  • Explores how data in multiple file formats and locations can be imported into R
  • Features a new chapter on Working with Large and Complex Datasets, presented to introduce the reader to the complexity of data organization
  • Concludes each chapter with multiple addenda, providing an opportunity to either introduce or reinforce important topics and associated functions that extend beyond R-based fundamentals
  • Provides all external datasets used in the book, for practice and retention of included concepts
  • Includes supplementary material: sn.pub/extras

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Table of contents (9 chapters)

Keywords

About this book

This book introduces the open source R software language that can be implemented in biostatistics for data organization, statistical analysis, and graphical presentation. In the years since the authors’ 2014 work Introduction to Data Analysis and Graphical Presentation in Biostatistics with R, the R user community has grown exponentially and the R language has increased in maturity and functionality. This updated volume expands upon skill-sets useful for students and practitioners in the biological sciences by describing how to work with data in an efficient manner, how to engage in meaningful statistical analyses from multiple perspectives, and how to generate high-quality graphics for professional publication of their research.

A common theme for research in the diverse biological sciences is that decision-making depends on the empirical use of data. Beginning with a focus on data from a parametric perspective, the authors address topics such as Student t-Tests for independent samples and matched pairs; oneway and twoway analyses of variance; and correlation and linear regression. The authors also demonstrate the importance of a nonparametric perspective for quality assurance through chapters on the Mann-Whitney U Test, Wilcoxon Matched-Pairs Signed-Ranks test, Kruskal-Wallis H-Test for Oneway Analysis of Variance, and the Friedman Twoway Analysis of Variance.     

To address the element of data presentation, the book also provides an extensive review of the many graphical functions available with R. There are now perhaps more than 15,000 external packages available to the R community. The authors place special emphasis on graphics using the lattice package and the ggplot2 package, as well as less common, but equally useful, figures such as bean plots, strip charts, and violin plots.

A robust package of supplementary material, as well as an introduction of the development of both R and the discipline of biostatistics, makes this ideal for novice learners as well as more experienced practitioners.

Reviews

“The strengths include the ideal analysis containing both graphical and statistical output as well as a variety of datasets … . the authors provide a number of R packages for obtaining the same results, such as graphics or statistics output. … Each chapter is so complete that it can be read in any order; learned readers will probably jump back and forth between the chapters. This book can be used for self-learning or teaching purpose on the subject.” (Shu-Hui Wen, Biometrics, Vol. 78 (2), July, 2022)

Authors and Affiliations

  • Senior Research Associate, Office of Institutional Effectiveness, Nova Southeastern University, Fort Lauderdale, USA

    Thomas W. MacFarland

  • Professor Emerita, Abraham S. Fischler College of Education, Nova Southeastern University, Fort Lauderdale, USA

    Jan M. Yates

About the authors

Thomas W. MacFarland, Ed.D., is Senior Research Associate (Office of Institutional Effectiveness) and Associate Professor (College of Computing and Engineering) at Nova Southeastern University, Fort Lauderdale, Florida. From his first experience with agricultural research as an Integrated Pest Management scout, Dr. MacFarland has been actively involved with research and statistical analyses for more than 40 years and has been a proponent for use of the R language since it first grew out of S.

Jan Yates, Ph.D., is Professor Emerita of Educational Media and Computer Science Education at Nova Southeastern University's Abraham S. Fischler College of Education in Fort Lauderdale, Florida. Since 2001, she has worked as associate professor and program professor in these content areas and in the areas of curriculum development, program assessment and review, and accreditation.

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