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Nutritional Management and Metabolic Aspects of Hyperhomocysteinemia

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  • © 2021

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Editors:
  1. Mostafa I. Waly

    1. Food Science and Nutrition, Sultan Qaboos University, Alkhod, Oman

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  • Addresses the biochemical and nutritional aspects of hyperhomocysteinemia in relation to increasing risk of chronic diseases
  • Covers newly updated information in the field of nutritional biochemistry and hyperhomocysteinemia
  • Provides a comprehensive link between hyperhomocysteinemia, oxidative stress, and human chronic disease

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. Signaling Pathways of Hyperhomocystenemia and Oxidative Stress

    • Mostafa I. Waly
    Pages 1-7

  3. Hyperhomocysteinemia and Cancer: The Role of Natural Products and Nutritional Interventions

    • Wamidh H. Talib, Muna Barakat, Lina T. Al Kury
    Pages 9-32

  4. Anti-inflammatory Role of Anthocyanins in the Prevention of Hyperhomocysteinemia-Mediated Cardiometabolic Diseases

    • Neeru Bhatt, Mostafa I. Waly, Amanat Ali
    Pages 33-49

  5. Metabolic Role of Hyperhomocysteinemia in the Etiology of Chronic Diseases

    • Sithara Suresh, Mostafa I. Waly
    Pages 51-68

  6. B-Vitamins Attenuates Preliminary Steps of Hyperhomocysteinemia and Colorectal Cancer

    • Mostafa I. Waly, Amanat Ali, Nejib Guizani
    Pages 69-76

  7. Hyperhomocysteinemia, B-Vitamins, and Coronary Artery Disease Risk

    • Amanat Ali, Mostafa I. Waly, Muhammad Athar Sadiq
    Pages 77-87

  8. Potential Role of Hyperhomocysteinemia in Prediabetes Etiology and Pathology

    • Mostafa I. Waly
    Pages 89-97

  9. Genetic Risk Factors in the Development of Hyperhomocysteinemia

    • Syed Tasleem Raza
    Pages 99-113

  10. Hyperhomocysteinemia and Risk of Cervical Cancer

    • Pushpendra D. Pratap, Syed Tasleem Raza, Sanju Pratap, Muneshwar Rajput
    Pages 115-123

  11. Medical Aspects of Hyperhomocystinemia and Neurological Disorders

    • Preeja Prabhakar, Sivaprasad Punnaveetil
    Pages 125-132

  12. Association Between Hyperhomocysteinemia and Human Chronic Diseases

    • Walaa M. R. El-Meidany
    Pages 133-156

  13. Hyperhomocysteinemia and Risk of Atherosclerosis, Cardiovascular Disease and Cancer: A Concise Update

    • Varna Taranikanti
    Pages 157-165

  14. The Causative Mechanisms of Hyperhomocysteinemia and Obesity

    • Ayah Rebhi Hilles, Syed Mahmood
    Pages 167-172

  15. The Importance of Obesity as a Risk Factor for Hyperhomocysteinemia: An Overview

    • Basma Al Yazeedi
    Pages 173-176

  16. Potential Role of Functional Foods and Antioxidants in Relation to Oxidative Stress and Hyperhomocysteinemia

    • Mona Miran, Maryam Salami, Zahra Emam-Djomeh
    Pages 177-197

  17. Nutritional Management of Hyperhomocysteinemia

    • Amany A. Salama
    Pages 199-213

  18. Antioxidants and Therapeutic Options of Hyperhomocysteinemia

    • Asma Ashraf Khan, Mahvish Ashraf
    Pages 215-224

  19. The Effects of B-Vitamins, Dietary Bioactive Agents and Functional Foods on Hyperhomocysteinemia

    • Amira O. Abd El-Azim
    Pages 225-241

  20. Bioactive Agents as a Novel Therapy of Hyperhomocysteinemia

    • Asma Ashraf Khan, Mahvish Ashraf
    Pages 243-248
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Keywords

About this book

Elevated blood concentrations of homocysteine, B vitamins deficiencies and oxidative stress are etiological factors for many human chronic diseases, yet the etiologic relationship of hyperhomocysteinemia to these disorders remains poorly understood. Clinical trials continue to support the notion that hyperhomocysteinemia is involved in the pathogenesis of oxidative stress and its associated impairment of cellular redox status. Antioxidants, phytochemicals, and bioactive agents are thought to be associated with the reduction of oxidative stress and reducing risk of chronic diseases, yet their role in preventing hyperhomocysteinemia-mediated oxidative stress has not been well covered in the literature. 

Nutritional Management and Metabolic Aspects and  of Hyperhomocysteinemia comprehensively covers the nutritional-based intervention for combating hyperhomocysteinemia-mediated oxidative stress, metabolic regulation of homocysteine-dependent transulfuration and transmethylation pathways, and the identification of novel biomarkers for early diagnosis of hyperhomocysteinemia. The main goal of this text is to address the biochemical and nutritional aspects of hyperhomocysteinemia in relation to increasing risk of chronic diseases, providing insight into the etiology of hyperhomocysteinemia and covering new research on the effective reduction and management of hyperhomocysteinemia-associated chronic diseases.

For researchers seeking a singular source for the understanding of the biochemical aspects and nutrition-based combat of hyperhomocysteinemia, its risk factors, preventive measures, and possible treatments currently available, this text provides all of the important needed information in up-to-date and comprehensive form. 



Editors and Affiliations

  • Food Science and Nutrition, Sultan Qaboos University, Alkhod, Oman

    Mostafa I. Waly

About the editor

Mostafa I. Waly is an Associate Professor in Food Science and Nutrition at Sultan Qaboos University in Alkhod, Oman

Bibliographic Information

  • Book Title: Nutritional Management and Metabolic Aspects of Hyperhomocysteinemia

  • Editors: Mostafa I. Waly

  • DOI: https://doi.org/10.1007/978-3-030-57839-8

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2021

  • Hardcover ISBN: 978-3-030-57838-1Published: 01 April 2021

  • Softcover ISBN: 978-3-030-57841-1Published: 02 April 2022

  • eBook ISBN: 978-3-030-57839-8Published: 31 March 2021

  • Edition Number: 1

  • Number of Pages: XV, 274

  • Number of Illustrations: 11 b/w illustrations, 12 illustrations in colour

  • Topics: Clinical Nutrition, Bioorganic Chemistry, Food Science

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