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  • © 2009

HIV and the Brain

New Challenges in the Modern Era

  • Summarizes the current state of knowledge regarding HIV and the brain
  • Primarily focuses on advanced age and HIV, international studies of HIV and the brain, and reviews the impact of long-term treatment of HIV
  • Provides the most comprehensive review of key clinical and research issues in contemporary HIV

Part of the book series: Current Clinical Neurology (CCNEU)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-xiv
  2. Neurocognitive Changes in AIDS: Evolution of Treatment of HIV Infection

    • Erna Milunka Kojic, Charles C.J. Carpenter
    Pages 1-8
  3. New Insights into HIV Neuropathogenesis

    • Tory P. Johnson, Avindra Nath
    Pages 17-27
  4. Neuropathological Findings Associated with Long-Term HAART

    • Iain C. Anthony, Jeanne E. Bell
    Pages 29-47
  5. Biomarkers of HIV-Related Central Nervous System Disease

    • Bruce James Brew, Scott Letendre
    Pages 49-73
  6. Neuroimaging Among HIV-Infected Patients: Current Knowledge and Future Directions

    • David F. Tate, Jared J. Conley, Dominik S. Meier, Bradford A. Navia, Ronald Cohen, Charles R.G. Guttmann
    Pages 75-107
  7. Youth with HIV/AIDS: Neurobehavioral Consequences

    • Susannah Allison, Pamela L. Wolters, Pim Brouwers
    Pages 187-211
  8. Co-Occurrence of HIV, Hepatitis C, and Substance Use Disorders: Effects on Brain Functioning

    • Raul Gonzalez, Phillip J. Quartana, Eileen M. Martin
    Pages 213-232
  9. The Functional Impact of HIV-Associated Neuropsychological Decline

    • Matthew J. Wright, Ellen Woo, Terry R. Barclay, Charles H. Hinkin
    Pages 233-248
  10. Adjunctive Therapy for Long-Term Support of Cognitive Impairment

    • Joshua T. Dearborn, Susan E. Maloney, Nicole Hicklin, Elizabeth M. Lane, Robert Paul
    Pages 249-266
  11. Opportunistic Infections in the Brain in Developing Countries

    • Marcus Tulius, T. Silva, Beatriz Grinsztejn
    Pages 293-317
  12. Impact of Clade Diversity on Neuropsychological Outcomes

    • Robert Paul, Ned Sacktor, Lucette Cysique, Bruce Brew, Victor Valcour
    Pages 319-329
  13. The Effects of Aging on HIV Disease

    • Robert C. Kalayjian, Lena Al-Harthi
    Pages 331-346
  14. Neuropsychology of Healthy Aging

    • Molly E. Zimmerman, Adam M. Brickman
    Pages 347-367
  15. Interactions Between Advanced Age and HIV Cognitive Impairment

    • Victor Valcour, Aaron M. McMurtray
    Pages 369-391
  16. Back Matter

    Pages 393-400

About this book

Within the last decade there have been a number of new and important areas of emphasis in HIV care and research, particularly in the context of brain involvement. Without question, clinical and research innovations in the modern era of the HIV pandemic warrant an update on HIV and the brain. Written by a panel of leading experts, HIV and the Brain: New Challenges in the Modern Era offers a clear picture of brain impairment associated with the virus with particular focus on three emerging areas including different genetic strains of the virus throughout the world, interactions between advanced age and HIV, and the impact of HIV on the brain in the context of chronic, long-term treatment with highly active antiretroviral therapy (HAART). HIV and the Brain: New Challenges in the Modern Era provides a comprehensive review of both basic science and clinical implications in these important areas of the disease. The text is of particular relevance to both research scientists and clinicians involved in HIV in the modern era.

Reviews

From the reviews:

“This book describes the impact of the AIDS virus on the brain and its relationship to the introduction of highly active antiretroviral therapy (HAART) in the mid-nineties. … intended for scientists researching AIDS and its impact on the brain, as well as for clinical care providers. … useful to those in the field of geriatrics involved with patients with AIDS and accompanying neurological deficits. Clinical care providers and clinical researchers will find the book informative … for treating patients with HIV in the modern era.” (Joseph I. Sirven, Doody’s Review Service, July, 2009)

“HIV and the Brain: New Challenges in the Modern Era is … for the broader medical community … . It provides relevant new information and highlights important factors to consider when one is dealing with individuals who have HIV/AIDS in the post-highly active antiretroviral therapy (HAART) era. … HIV and the Brain discusses guidelines for proper assessment, including the increasing need for a comprehensive neuropsychological battery … for specific and/or subtle cognitive deficits to manifest rather than global impairment.” (Charles Golden and Christine Corsun-Ascher, PsycCRITIQUES, December, 2009)

“The primary audience is intended to be clinicians … hope that the book will also be useful to basic and clinical researchers. … significant interest to clinicians … . provides a wide range of information that is important to clinicians and researchers alike. Written by expert international authors, it represents a major contribution to HIV medicine and should be an essential part of the reference collection of all HIV care providers as well as scientists working on the neurological complications of HIV infection.” (Zelalem Temesgen, Clinical Infectious Diseases, Vol. 49, November, 2009)

“This book will definitely appeal to its target audience of clinicians and both basic and clinical researchers … .In summary, this book is excellent–it is well-organized, easy to read, and interesting. … Clinicians from a wide variety of disciplines and researchers will certainly benefit from and enjoy having this book in their personal library. While neuroradiologists will also enjoy reading this book and will definitely value its content … .” (American Journal of Neuroradiology, November, 2009)

Editors and Affiliations

  • Department of Psychology Behavioral Neuroscience, University of Missouri – St. Louis, St. Louis, U.S.A.

    Robert H. Paul

  • Johns Hopkins Bayview Medical Center, Johns Hopkins University School of Medicine, Baltimore, U.S.A.

    Ned Charlton Sacktor

  • Department of Geriatric Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, U.S.A.

    Victor Valcour

  • Memory and Aging Center Department of Neurology, UCSF, San Francisco, U.S.A.

    Victor Valcour

  • The Miriam Hospital, Alpert Medical School of Brown University, Providence, U.S.A.

    Karen Tokie Tashima

Bibliographic Information

  • Book Title: HIV and the Brain

  • Book Subtitle: New Challenges in the Modern Era

  • Editors: Robert H. Paul, Ned Charlton Sacktor, Victor Valcour, Karen Tokie Tashima

  • Series Title: Current Clinical Neurology

  • DOI: https://doi.org/10.1007/978-1-59745-434-6

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Humana Press 2009

  • Hardcover ISBN: 978-1-934115-08-4Published: 09 March 2009

  • eBook ISBN: 978-1-59745-434-6Published: 20 April 2009

  • Series ISSN: 1559-0585

  • Series E-ISSN: 2524-4043

  • Edition Number: 1

  • Number of Pages: X, 350

  • Topics: Infectious Diseases, Neurology, Internal Medicine, Immunology, Pain Medicine

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access