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  • © 2010

Molecular Basis for Therapy of AIDS-Defining Cancers

  • Will provide an update of the latest treatments for AIDS defining cancers, a scientific rationale for established treatments and a review of novel molecularly-targeted treatment options, which have passed pre-clinical testing

  • Includes supplementary material: sn.pub/extras

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-xii
  2. The Epidemiology of Cancer in People with HIV

    • Andrew E. Grulich, Diego Serraino, Denise Whitby
    Pages 1-16
  3. Immunology of HIV-Associated Kaposi Sarcoma

    • Ashok Cattamanchi, Corey Casper
    Pages 59-78
  4. Targeting Signal Transduction Pathways for the Treatment of Kaposi Sarcoma

    • Janet L. Douglas, Henry B. Koon, Ashlee V. Moses
    Pages 79-93
  5. Role of NF-κB Inhibitors in HIV-Related Malignancies

    • Erin Gourley Reid, Dirk P. Dittmer
    Pages 95-110
  6. Metronomic Therapy for HIV-Associated Malignancies

    • Rosemary Rochford, Scot C. Remick
    Pages 199-210
  7. Targeting EGFR in HPV-Associated Cancer

    • Joseph A. Sparano, Missak Haigentz, Mark H. Einstein
    Pages 211-234
  8. Back Matter

    Pages 247-256

About this book

Cancer incidences increase in people living with HIV/AIDS. Over 2 million people currently live with HIV/AIDS in the US. This number will increase as HAART prolongs the average lifespan and as (at least in some states) the number of new HIV infections increase again. As this population ages their incidence rates for cancer will increase, as well.

Recently, new rational targets for cancer therapy have emerged. But their application to the care of HIV+ patients is slow, because of concerns about the weakened immune status of the patients, because of possible drug interactions with HAART and because some of the AIDS defining cancer are rare.

Editors and Affiliations

  • Lineberger Comprehensive, Cancer Center, University of North Carolina, Chapel Hill, USA

    Dirk P. Dittmer

  • Cancer Center, Memorial Sloan-Kettering, New York, USA

    Susan E. Krown

Bibliographic Information

  • Book Title: Molecular Basis for Therapy of AIDS-Defining Cancers

  • Editors: Dirk P. Dittmer, Susan E. Krown

  • DOI: https://doi.org/10.1007/978-1-4419-1513-9

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media, LLC 2010

  • Hardcover ISBN: 978-1-4419-1512-2Published: 08 June 2010

  • Softcover ISBN: 978-1-4899-8200-1Published: 06 September 2014

  • eBook ISBN: 978-1-4419-1513-9Published: 14 June 2010

  • Edition Number: 1

  • Number of Pages: XIII, 256

  • Topics: Cancer Research, Pharmacology/Toxicology, Infectious Diseases

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access