Overview
- Uniquely focuses its attention on how the same molecules can have favorable or noxious effects depending on location, level and timing
- Each chapter focuses is devoted to one particular molecule or oxidant/antioxidant system
- Each chapter provides a state of the art review of the current understanding regarding both positive and negative actions of the system under review
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Table of contents (17 chapters)
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Front Matter
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Old Players
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New Players
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Back Matter
Keywords
About this book
Oxidants, like other aspects of life, involves tradeoffs. Oxidants, whether intentionally produced or by-products of normal metabolism can either mediate a variety of critical biological processes but when present inappropriately cause extensive damage to biological molecules (DNA, proteins, and lipids). These effects can lead to either damage that is a major contributor to aging and degenerative diseases (or to other diseases such as cancer, cardiovascular disease, immune-system decline, brain dysfunction, and cataracts) or normal physiological function- tissue repair, defense against pathogens and cellular proliferation. On the other hand the body is equipped with a complex antioxidant/oxidant handling system which includes both enzymatic and nonenzymatic (i.e. small molecules such as flavonoids, ascorbate, tocopherol, and carotenoids) produced endogenously or derived from the diet. This book focuses on how the same molecules can have favorable or noxious effects depending on location, level and timing.
Each chapter focuses on one particular molecule or oxidant/antioxidant system and provides a state of the art review of the current understanding regarding both positive and negative actions of the system under review.
Editors and Affiliations
Bibliographic Information
Book Title: Oxidants in Biology
Book Subtitle: A Question of Balance
Editors: Giuseppe Valacchi, Paul A. Davis
DOI: https://doi.org/10.1007/978-1-4020-8399-0
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media B.V. 2008
Hardcover ISBN: 978-1-4020-8398-3Published: 25 August 2008
Softcover ISBN: 978-90-481-7867-4Published: 19 October 2010
eBook ISBN: 978-1-4020-8399-0Published: 06 June 2008
Edition Number: 1
Number of Pages: VIII, 328
Topics: Pharmacology/Toxicology, Chemistry/Food Science, general, Cell Biology