Overview
- Novel topic in bio-medical research
- Fundamental and practical issues related to cancer therapy
- Of interest to students, researchers and physicians
Part of the book series: The Tumor Microenvironment (TTME, volume 1)
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Table of contents (10 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Cancer cells are continuously interacting with the immune system of the host. These interactions can be regarded as a double edged sword. On the one hand, innate and adaptive immune responses act to protect the host by attempting rejection of the tumor. On the other hand, inflammatory cells and proteins stimulate multiplication and dissemination of cancer cells, thereby accelerating the progression of the disease. Traditionally, the interplay between cancer cells and host immunity has been studied systemically, with no particular attention to the site at which a given tumor develops. Recent studies, however, indicate that the tumor microenvironment is unique in providing both supportive and inhibitory factors that determine the fate of the tumor and its host. Accordingly, microenvironmental immunity that operates inside and around a tumor plays a crucial role in cancer development and progression. The aim of the present volume is to compile reviews on innate and adaptive immune responses at the tumor microenvironment with emphasis on positive and negative outcomes that affect the progression of the disease. These reviews have been solicited from experts in the field who published original research studies focusing on these issues.
Editors and Affiliations
Bibliographic Information
Book Title: Innate and Adaptive Immunity in the Tumor Microenvironment
Editors: Eitan Yefenof
Series Title: The Tumor Microenvironment
DOI: https://doi.org/10.1007/978-1-4020-6750-1
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media B.V. 2008
Hardcover ISBN: 978-1-4020-6749-5Published: 04 December 2007
Softcover ISBN: 978-90-481-7713-4Published: 23 November 2010
eBook ISBN: 978-1-4020-6750-1Published: 20 December 2007
Edition Number: 1
Number of Pages: XII, 212
Topics: Cancer Research, Oncology, Immunology, Cell Biology, Biomedicine general