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Transgenesis and the Management of Vector-Borne Disease

  • Book
  • © 2008

Overview

Editors:
  1. Serap Aksoy

    1. Division of Epidemiology and Microbial Diseases, Yale University School of Public Health, New Haven, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 627)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xviii
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  2. Perspectives on the State of Insect Transgenics

    • David A. O’Brochta, Alfred M. Handler
    Pages 1-18

  3. Alphavirus Transducing Systems

    • Brian D. Foy, Ken E. Olson
    Pages 19-34

  4. Paratransgenesis Applied for Control of Tsetse Transmitted Sleeping Sickness

    • Serap Aksoy, Brian Weiss, Geoffrey Attardo
    Pages 35-48

  5. Bacteria of the Genus Asaia: A Potential Paratransgenic Weapon Against Malaria

    • Guido Favia, Irene Ricci, Massimo Marzorati, Ilaria Negri, Alberto Alma, Luciano Sacchi et al.
    Pages 49-59

  6. Proposed Uses of Transposons in Insect and Medical Biotechnology

    • Peter Atkinson W.
    Pages 60-70

  7. The Yin and Yang of Linkage Disequilibrium: Mapping of Genes and Nucleotides Conferring Insecticide Resistance in Insect Disease Vectors

    • William C. Black IV, Norma Gorrochetegui-Escalante, Nadine P. Randle, Martin J. Donnelly
    Pages 71-83

  8. Impact of Technological Improvements on Traditional Control Strategies

    • Mark Q. Benedict, Alan S. Robinson
    Pages 84-92

  9. Insect Population Suppression Using Engineered Insects

    • Luke Alphey, Derric Nimmo, Sinead O’Connell, Nina Alphey
    Pages 93-103

  10. Wolbachia- Based Technologies for Insect Pest Population Control

    • Kostas Bourtzis
    Pages 104-113

  11. Using Predictive Models to Optimize Wolbachia-Based Strategies for Vector-Borne Disease Control

    • Jason L. Rasgon
    Pages 114-125

  12. Modifying Insect Population Age Structure to Control Vector-Borne Disease

    • Peter E. Cook, Conor J. McMeniman, Scott L. O’Neill
    Pages 126-140

  13. Technological Advances to Enhance Agricultural Pest Management

    • Thomas A. Miller, Carol R. Lauzon, David J. Lampe
    Pages 141-150

  14. Applications of Mosquito Ecology for Successful Insect Transgenesis-Based Disease Prevention Programs

    • Thomas W. Scott, Laura C. Harrington, Bart G. J. Knols, Willem Takken
    Pages 151-168

  15. Back Matter

    Pages 169-171
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Keywords

About this book

Parasitic, bacterial and viral agents continue to challenge the welfare of humans, livestock, wild life and plants worldwide. The public health impact and financial consequences of these diseases are particularly hard on the already overburdened economies of developing countries especially in the tropics. Many of these disease agents utilize insect hosts (vectors) to achieve their transmission to mammals. In the past, these diseases were largely controlled by insecticide-based vector reduction strategies. Now, many of these diseases have reemerged in the tropics, recolonizing their previous range, and expanding into new territories previously not considered to be endemic. Habitat change, irrigation practices, atmospheric and climate change, insecticide and drug resistance as well as increases in global tourism, human traffic and commercial activities, have driven the reemergence and spread of vector borne diseases. While these diseases can be controlled through interventions aimed at both their vertebrate and invertebrate hosts, no effective vaccines exist, and only limited therapeutic prospects are available for their control in mammalian hosts. Molecular technologies such as transgenesis, which is the subject of this book, stand to increase the toolbox and benefit disease management strategies.

Editors and Affiliations

  • Division of Epidemiology and Microbial Diseases, Yale University School of Public Health, New Haven, USA

    Serap Aksoy

Bibliographic Information

  • Book Title: Transgenesis and the Management of Vector-Borne Disease

  • Editors: Serap Aksoy

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-0-387-78225-6

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2008

  • Hardcover ISBN: 978-0-387-78224-9Published: 19 March 2008

  • Softcover ISBN: 978-1-4419-2682-1Published: 29 November 2010

  • eBook ISBN: 978-0-387-78225-6Published: 21 August 2008

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XVIII, 171

  • Topics: Genetic Engineering, Biomedicine general

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