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  • © 2005

Proteomics of Spermatogenesis

Authors:

  • There is an urgent need to classify proteins of spermatogenic cells with a view of their functions, and their applications in the regulation of fertility and in understanding infertility. The understanding of structural properties of male germ cell specific proteins can offer vulnerable points for targeted intervention in testis without generalized effects on stages of spermatogenesis

  • Besides targeted action in male germ cells, sperm specific proteins and polypeptides may offer potential application in the development of a contraceptive vaccine in males and females. Therefore, this monograph will focus on the description of specialized proteins, which are dominantly and/or specifically expressed in germ cells and finally localized in spermatozoa

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Table of contents (34 chapters)

  1. Front Matter

    Pages i-xxvi
  2. Spermatogenesis

    • G. S. Gupta
    Pages 1-20
  3. Paracrine Role of Sertoli Cell

    • G. S. Gupta
    Pages 21-46
  4. Homeostasis of Germ Cells and Apoptosis

    • G. S. Gupta
    Pages 97-110
  5. Nuclear Skeleton Proteins: Non-Histones

    • G. S. Gupta
    Pages 111-136
  6. Microtubules

    • G. S. Gupta
    Pages 167-190
  7. Microtubule Based Motor Proteins

    • G. S. Gupta
    Pages 191-210
  8. Cell Cycle Components

    • G. S. Gupta
    Pages 235-260
  9. Isoproteins in DNA Synthesis

    • G. S. Gupta
    Pages 261-278
  10. DNA Repair and Recombination

    • G. S. Gupta
    Pages 279-302
  11. Transcriptional Control

    • G. S. Gupta
    Pages 303-322
  12. Proto-Oncoproteins

    • G. S. Gupta
    Pages 377-404
  13. Protein Kinases

    • G. S. Gupta
    Pages 439-492

About this book

Recent developments of experimental techniques in cellular and molecular biology have made it possible to understand the molecular biology of male gametogenesis in greater detail. This book focuses on the description of specialized proteins, which are dominantly and/or specifically expressed in germ cells and localized in spermatozoa. There is an urgent need to classify proteins of spermatogenic cells with a view of their functions, and their applications in the regulation of fertility and in understanding infertility. The understanding of structural properties of male germ cell specific proteins can offer vulnerable points for targeted intervention in testis without generalized effects on stages of spermatogenesis. Besides targeted action in male germ cells, sperm specific proteins and polypeptides may also offer potential application in the development of a contraceptive vaccine.

Authors and Affiliations

  • Department of Biophysics, Panjab University, Chandigarh, India

    G. S. Gupta

About the author

Dr. Gupta is a former Professor and Chairman of the Department of Biophysics, Panjab University, Chandigarh, India. His primary areas of research are molecular and cellular biology, reproductive biology/reproductive immunology, enzymology/enzyme technology, and radiation biology.

As a visiting researcher, he has worked at many institutions, including Northwestern University in Evanston, IL, the Center of Immunopathology and Experimental Immunology, INSERM, and the Center of Cytogenics and Immunogenetics, INSERM.

He has been honored by various Indian agencies such as Council of Scientific and Industrial Research (CSIR), University Grants Commission (UGC), Indian Council of Medical Research (ICMR), and Department of Science and Technology (DST).

Professor Gupta has made significant research contribution in the field of Reproductive Molecular Biology and Molecular Radiation Biology and published 120 original research articles and reviews in international journals.

He is the recipient of several awards and international fellowships including a WHO fellowship and the INSERM fellowship. Indian Council of Medical Research has honored him by conferring Swaran Kanta Dingley Oration Award of 1993 for his research contribution and extending knowledge in male reproduction. Associated with several national and international scientific societies, he has chaired scientific sessions and delivered invited lectures at national and International conferences.

Professor G.S. Gupta holds master’s degrees in Physical Chemistry and Biochemistry from Lucknow University, Lucknow, and a Ph.D. in Biophysics from Panjab University, Chandigarh (India).

Bibliographic Information

  • Book Title: Proteomics of Spermatogenesis

  • Authors: G. S. Gupta

  • DOI: https://doi.org/10.1007/0-387-27655-6

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag US 2005

  • Hardcover ISBN: 978-0-387-25398-5Published: 26 May 2005

  • eBook ISBN: 978-0-387-27655-7Published: 02 July 2006

  • Edition Number: 1

  • Number of Pages: XVI, 855

  • Topics: Proteomics, Cell Biology

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access