1. Molecular modeling studies on 3,4-dihydroquinazolines as trypanothione reductase inhibitors using 3D-QSAR and docking approaches

   • Zhi-Xiong Ruan
   • De-Sheng Huangfu
   • Wei-Min Chen

   Original Research 27 November 2012 Pages: 3541 - 3555

   

2. Synthesis, antioxidant, and antitumor evaluation of certain new N-substituted-2-amino-1,3,4-thiadiazoles

   • Wafaa S. Hamama
   • Moustafa A. Gouda
   • Hanafi H. Zoorob

   Original Research 27 November 2012 Pages: 3556 - 3565

   

3. Synthesis of some new 3,5-diamino-4-(4′-fluorophenylazo)-1-aryl/heteroarylpyrazoles as antimicrobial agents

   • Ranjana Aggarwal
   • Virender Kumar
   • Vinod Kumar

   Original Research 27 November 2012 Pages: 3566 - 3573

   

4. Evaluating anti-Toxoplasma gondii activity of new serie of phenylsemicarbazone and phenylthiosemicarbazones in vitro

   • Marco Antônio G. B. Gomes
   • Laís P. Carvalho
   • Edmilson J. Maria

   Original Research 27 November 2012 Pages: 3574 - 3580

   

5. Drug interactions and synthesis of cefpirome with hypoglycemic agents

   • Muhammad Nawaz
   • Muhammad Saeed Arayne
   • Najma Sultana

   Original Research 28 November 2012 Pages: 3581 - 3588

   

6. Challenges in docking 2′-hydroxy and 2′,4′-dihydroxychalcones into the binding site of ALR2

   • Sorin I. Avram
   • Luminita Crisan
   • Ludovic G. Kurunczi

   Original Research 28 November 2012 Pages: 3589 - 3605

   

7. Benzimidazole derivatives: synthesis, leishmanicidal effectiveness, and molecular docking studies

   • Awais Shaukat
   • Hira M. Mirza
   • Farzana L. Ansari

   Original Research 28 November 2012 Pages: 3606 - 3620

   

8. Novel salicylamide derivatives incorporating neonicotinoid pharmacophore: design, synthesis, characterization, and biological evaluation

   • Shaoyong Ke
   • Zhigang Zhang
   • Ziwen Yang

   Original Research 28 November 2012 Pages: 3621 - 3628

   

9. Antimicrobial and antiurease activities of newly synthesized morpholine derivatives containing an azole nucleus

   • Hakan Bektaş
   • Şule Ceylan
   • Bahar Bilgin Sökmen

   Original Research Open access 29 November 2012 Pages: 3629 - 3639

10. Non-imidazole histamine H₃ ligands: part V. synthesis and preliminary pharmacological investigation of 1-[2-thiazol-4-yl- and 1-[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propylpiperazine derivatives

    • Roman Guryn
    • Marek Staszewski
    • Krzysztof Walczyński

    Original Research Open access 29 November 2012 Pages: 3640 - 3652

    

11. Synthesis, molecular docking studies, and in vitro screening of sulfanilamide-thiourea hybrids as antimicrobial and urease inhibitors

    • Aamer Saeed
    • Sumera Zaib
    • Jamshed Iqbal

    Original Research 29 November 2012 Pages: 3653 - 3662

    

12. Synthesis of new quinoline-2-pyrazoline-based thiazolinone derivatives as potential antimicrobial agents

    • N. C. Desai
    • V. V. Joshi
    • K. M. Rajpara

    Original Research 29 November 2012 Pages: 3663 - 3674

    

13. Syntheses and in vitro biological screening of 1-aryl-10H-[1,2,4]triazolo[3′,4′:3,4][1,2,4]triazino[5,6-b]indoles

    • Kuldip Upadhyay
    • Atul Manvar
    • Anamik Shah

    Original Research 30 November 2012 Pages: 3675 - 3686

    

14. Erratum to: Syntheses and in vitro biological screening of 1-aryl-10H-[1,2,4]triazolo[3′,4′:3,4][1,2,4]triazino[5,6-b]indoles

    • Kuldip Upadhyay
    • Atul Manvar
    • Paolo La Colla

    Erratum 29 January 2013 Pages: 3687 - 3687

15. Antibacterial and antifungal screening of newly synthesized benzimidazole-clubbed chalcone derivatives

    • Kalpesh Parikh
    • Deepkumar Joshi

    Original Research 30 November 2012 Pages: 3688 - 3697

    

16. Trypsin inhibitory potential and microbial transformation of rutin isolated from Citrus sinensis

    • Muhammad Asam Raza
    • Durre Shahwar

    Original Research 30 November 2012 Pages: 3698 - 3702

    

17. Synthesis, antimalarial-, and antibacterial activity evaluation of some new 4-aminoquinoline derivatives

    • Mithun Rudrapal
    • Dipak Chetia
    • Anil Prakash

    Original Research 01 December 2012 Pages: 3703 - 3711

    

18. Synthesis and cytotoxicity of novel 6H-indolo[2,3-b]quinoxaline derivatives

    • Sreenivas Avula
    • Jayaram Reddy Komsani
    • Srigiridhar Kotamraju

    Original Research 01 December 2012 Pages: 3712 - 3718

19. Synthesis and biological evaluation of novel condensed pyrimidinylmethylsulfinylbenzimidazoles as antiulcer agent

    • Prashik B. Dudhe
    • Kishor S. Jain
    • Muthu K. Kathiravan

    Original Research 04 December 2012 Pages: 3719 - 3727

    

20. Chem-bioinformatics and in vitro approaches for candidate optimization: a case study of NSC745689 as a promising antitumor agent

    • Prajwal P. Nandekar
    • Khaled M. Tumbi
    • Abhay T. Sangamwar

    Original Research 04 December 2012 Pages: 3728 - 3742

    

21. Synthesis of novel 4-thiazolidione derivatives as antibacterial agents against drug-resistant Staphylococcus epidermidis

    • Dan Zhao
    • Huayong Liu
    • Shiqing Han

    Original Research 07 December 2012 Pages: 3743 - 3750

    

22. Apoptotic effects of some carbazole derivatives on lung carcinoma and glioma cell lines

    • Gülşen Akalın Çiftçi
    • Halide Edip Temel
    • Lütfi Genç

    Original Research 09 December 2012 Pages: 3751 - 3759

    

23. Synthesis and biological evaluation of novel hydroquinone dimethyl ethers as potential anticancer and antimicrobial agents

    • Ibrahim Chaaban
    • El Sayeda M. El Khawass
    • Abeer E. Abdel Wahab

    Original Research 09 December 2012 Pages: 3760 - 3778

    

24. Novel 2-(E)-substituted benzylidene-6-(N-substituted aminomethyl)cyclohexanones and cyclohexanols as analgesic and anti-inflammatory agents

    • Dan Liu
    • Weishe Yu
    • Linxiang Zhao

    Original Research 09 December 2012 Pages: 3779 - 3786

25. Synthesis of some new indolo[2,3-c]isoquinolinyl pyrazoles, -1,3,4-oxadiazoles and their biological activities

    • Anand R. Saundane
    • Vaijinath A. Verma
    • Katkar Vijaykumar

    Original Research 09 December 2012 Pages: 3787 - 3793

    

26. In silico design of peptidomimetics for PKC-β II inhibition: perspectives for diabetic cardiomyopathy therapy

    • Shishir Rohit
    • Anand Balupuri
    • M. Elizabeth Sobhia

    Original Research 09 December 2012 Pages: 3794 - 3801

    

27. Docking, synthesis, and pharmacological investigation of novel substituted thiazole derivatives as non-carboxylic, anti-inflammatory, and analgesic agents

    • S. N. Thore
    • Sunil V. Gupta
    • Kamalkishor G. Baheti

    Original Research 11 December 2012 Pages: 3802 - 3811

    

28. Pharmacophore modeling, 3D-QSAR, and molecular docking study on naphthyridine derivatives as inhibitors of 3-phosphoinositide-dependent protein kinase-1

    • Palani Kirubakaran
    • Karthikeyan Muthusamy
    • Selvaraman Nagamani

    Original Research 11 December 2012 Pages: 3812 - 3822

    

29. Isolation of terrestribisamide from Peltophorum pterocarpum (DC.) Baker ex. K. Heyne and its antimicrobial, antioxidant, and cytotoxic activities

    • M. Karunai Raj
    • C. Balachandran
    • A. Vijayakumar

    Original Research 11 December 2012 Pages: 3823 - 3830

    

30. Microwave-assisted synthesis of novel 4H-chromene derivatives bearing 2-aryloxyquinoline and their antimicrobial activity assessment

    • Chetan B. Sangani
    • Nimesh M. Shah
    • Ranjan G. Patel

    Original Research 12 December 2012 Pages: 3831 - 3842

31. Design and synthesis of new N-substituted amino methyl-[1,2,3] triazolyl moieties of fluoroquinolones as antibacterial agents

    • G. Govinda Rajulu
    • Halehatty S. Bhojya Naik
    • Kesavan Poonimangadu Koppolu

    Original Research 13 December 2012 Pages: 3843 - 3856

    

32. Synthesis and cytotoxic activity of diaryl urea derivatives with a 4-methylpiperazinylcarbonyl moiety

    • Wei Xuan
    • Wen Ding
    • San-qi Zhang

    Original Research 13 December 2012 Pages: 3857 - 3862

    

33. Synthesis, antitubercular activity, and QSAR analysis of substituted nitroaryl analogs: chalcone, pyrazole, isoxazole, and pyrimidines

    • Revathi A. Gupta
    • Satish G. Kaskhedikar

    Original Research 14 December 2012 Pages: 3863 - 3880

    

34. Synthesis and biologic evaluation of new 3-phenoxyazetidin-2-one derivatives as selective cyclooxygenase-2 inhibitors

    • H. Arefi
    • A. Zarghi

    Original Research 15 December 2012 Pages: 3881 - 3887

    

35. Synthesis and comparative bioefficacy of N-(1-phenethyl-4-piperidinyl)propionanilide (fentanyl) and its 1-substituted analogs in Swiss albino mice

    • Pradeep Kumar Gupta
    • Shiv Kumar Yadav
    • Rahul Bhattacharya

    Original Research 15 December 2012 Pages: 3888 - 3896

    

36. Design, synthesis, and cytotoxic activities of new 2,4,5-triarylimidazoles

    • A. Zarghi
    • S. Arfaei
    • F. H. Shirazi

    Original Research 15 December 2012 Pages: 3897 - 3904

    

37. Virtual screening and biochemical evaluation of the inhibitors of dual-specificity phosphatase 26

    • Hwangseo Park
    • Ayoung Kyung
    • Dae Gwin Jeong

    Original Research 15 December 2012 Pages: 3905 - 3910

    

38. Antitumour activity of 5-[(2E)-1-(1H-benzimidazol-2-yl)-3-substituted phenylprop-2-en-1-ylidene] pyrimidine-2,4,6(1H,3H,5H)-triones against Dalton’s ascitic lymphoma in mice

    • Bijo Mathew
    • Jerad Suresh
    • Devaraji Vinod

    Original Research 15 December 2012 Pages: 3911 - 3917

    

39. Novel PCU cage diol peptides as potential targets against wild-type CSA HIV-1 protease: synthesis, biological screening and molecular modelling studies

    • Rajshekhar Karpoormath
    • Yasien Sayed
    • Glenn E. M. Maguire

    Original Research 18 December 2012 Pages: 3918 - 3933

    

40. Antibacterial and antifungal oxovanadium(IV) complexes of triazole-derived Schiff bases

    • Sajjad H. Sumrra
    • Zahid H. Chohan

    Original Research 18 December 2012 Pages: 3934 - 3942

    

41. Synthesis and antitumor activity of new pyrido[2,3-d]pyrimidine derivatives

    • Magdy M. Gineinah
    • Magda N. A. Nasr
    • Walaa M. El-Husseiny

    Original Research 18 December 2012 Pages: 3943 - 3952

    

42. Inhibition of Cathepsin D protease activity by Punica granatum fruit peel extracts, isolates, and semisynthetic analogs

    • Amit K. Chaturvedi
    • Suaib Luqman
    • Arvind S. Negi

    Original Research 18 December 2012 Pages: 3953 - 3958

    

43. Thiourea and thioether derivatives of sorafenib: synthesis, crystal structure, and antiproliferative activity

    • Jianwen Yao
    • Jing Chen
    • Wenfang Xu

    Original Research 18 December 2012 Pages: 3959 - 3968

    

44. Synthesis and biologic activities of some novel heterocyclic chalcone derivatives

    • Punita Sharma
    • Suresh Kumar
    • Naresh K. Satti

    Original Research 18 December 2012 Pages: 3969 - 3983

    

45. Anti-inflammatory and analgesic activities of a new cucurbitacin isolated from Citrullus colocynthis seeds

    • Belsem Marzouk
    • Mohamed Ali Mahjoub
    • Zohra Marzouk

    Original Research 18 December 2012 Pages: 3984 - 3990

    

46. Synthesis of d-amino acid peptides and their effect on beta-amyloid aggregation and toxicity in transgenic Caenorhabditis elegans

    • Seema Jagota
    • Jayakumar Rajadas

    Original Research 19 December 2012 Pages: 3991 - 4000

    

47. Synthesis and biological evaluation of new [1,3,4]thiadiazepino[7,6-b]quinolin-2-amines as potent anti-microbial agents

    • Hasnain Muhammad Raza
    • Nada-E-Ali Rizvi
    • Mazhar Iqbal

    Original Research 19 December 2012 Pages: 4001 - 4015

    

48. Cytotoxicity and QSAR study of (thio)ureas derived from phenylalkylamines and pyridylalkylamines

    • Ratchanok Pingaew
    • Pan Tongraung
    • Virapong Prachayasittikul

    Original Research 19 December 2012 Pages: 4016 - 4029

    

49. In vitro cytotoxicity, antimicrobial, and metal-chelating activity of triterpene saponins from tea seed grown in Kangra valley, India

    • Robin Joshi
    • Swati Sood
    • Ashu Gulati

    Original Research 19 December 2012 Pages: 4030 - 4038

    

50. Partition coefficient determination of a series of isoindolines-2-substituted and its correlation with their antiproliferative activity on HeLa cells

    • Cynthia R. Trejo Muñoz
    • Teresa Mancilla Percino
    • José G. Trujillo Ferrara

    Original Research 20 December 2012 Pages: 4039 - 4045