1. Synthesis, characterization, and antimicrobial activity of copper(II) complexes with N,N′-propanediyl-bis-benzenesulfonamide and N,N′-ethanediyl-bis-2-methylbenzenesulfonamide

   • Saliha Alyar
   • Neslihan Özbek
   • Nurcan Karacan

   Original Research 14 September 2012 Pages: 2051 - 2060

   

2. Synthesis and biological evaluation of novel 4,5-dihydropyrazole derivatives as potent anticancer and antimicrobial agents

   • Y. Rajendra Prasad
   • G. V. Suresh Kumar
   • S. M. Chandrashekar

   Original Research 02 September 2012 Pages: 2061 - 2078

3. In vitro biological activities of new heterocyclic chalcone derivatives

   • Chenna Govindaraju Darshan Raj
   • Balladaka Kunchanna Sarojini
   • Ramappa Ragavendra

   Original Research 18 September 2012 Pages: 2079 - 2087

   

4. Isolation of long-chain esters from the rhizome of Polygonatum verticillatum by potent tyrosinase inhibition

   • Haroon Khan
   • Muhammad Saeed
   • Rukhsana Ghaffar

   Original Research 02 September 2012 Pages: 2088 - 2092

   

5. Synthesis of damnacanthal, a naturally occurring 9,10-anthraquinone and its analogues, and its biological evaluation against five cancer cell lines

   • Koushik Saha
   • Kok Wai Lam
   • Nordin H. Lajis

   Original Research 13 September 2012 Pages: 2093 - 2104

   

6. Synthesis and antitumor studies of novel benzopyrano-1,2,3-selenadiazole and spiro[benzopyrano]-1,3,4-thiadiazoline derivatives

   • S. I. El-Desoky
   • F. A. Badria
   • A. H. Abdel-Rahman

   Original Research 31 August 2012 Pages: 2105 - 2114

   

7. Bioactive xanthones with effect on P-glycoprotein and prediction of intestinal absorption

   • Emília Sousa
   • Andreia Palmeira
   • Madalena Pinto

   Original Research 31 August 2012 Pages: 2115 - 2123

   

8. Comprehensive structure–activity relationship analysis of substituted 5-(biphenyl-4-ylmethyl) pyrazoles derivatives as AT₁ selective angiotensin II receptor antagonists: 2D and kNNMFA QSAR approach

   • Mukesh C. Sharma
   • D. V. Kohli

   Original Research 23 September 2012 Pages: 2124 - 2138

   

9. Molecular docking studies on analogues of quercetin with d-alanine:d-alanine ligase of Helicobacter pylori

   • Salam Pradeep Singh
   • Rocktotpal Konwarh
   • Niranjan Karak

   Original Research 07 September 2012 Pages: 2139 - 2150

   

10. Structure–activity relationship study of thiosemicarbazones on an African trypanosome: Trypanosoma brucei brucei

    • Houssou Raymond Fatondji
    • Salomé Kpoviessi
    • Georges Coffi Accrombessi

    Original Research 05 September 2012 Pages: 2151 - 2162

    

11. Synthesis, in vitro cytotoxicity, and antibacterial studies of new asymmetric bis-1,2,4-triazoles

    • Rohit Singh
    • Gurubasavaraj V. Pujar
    • V. M. Chandrashekar

    Original Research 04 September 2012 Pages: 2163 - 2173

    

12. Pharmacophore model generation and 3D-QSAR analysis of N-acyl and N-aroylpyrazolines for enzymatic and cellular B-Raf kinase inhibition

    • Omprakash Tanwar
    • Akranth Marella
    • Mymoona Akhtar

    Original Research 05 September 2012 Pages: 2174 - 2187

    

13. Synthesis, characterization, and pharmacological evaluation of benzothiopyran derivatives as a novel class of calcium channel blockers

    • Rajkumari Nalwaya
    • Arvind Sahai
    • Gaurav Sarsodia

    Original Research 19 September 2012 Pages: 2188 - 2195

    

14. Synthesis and insect antifeedant activity of stilbene derivatives against Brontispa longissima Larvae

    • Ying-Qian Liu
    • Xiao-Jing Li
    • Liu Yang

    Original Research 06 September 2012 Pages: 2196 - 2206

    

15. Antitumor and antileishmanial evaluation of novel heterocycles derived from quinazoline scaffold: a molecular modeling approach

    • Daisy H. Fleita
    • Rafat M. Mohareb
    • Ola K. Sakka

    Original Research 09 September 2012 Pages: 2207 - 2221

    

16. Simultaneous determination of flavonoids in Oroxylum indicum by RP-HPLC

    • Akhilesh K. Yadav
    • N. Manika
    • Madan M. Gupta

    Original Research 06 September 2012 Pages: 2222 - 2227

    

17. Synthesis and hypoglycemic activity evaluation of rhein amide derivatives

    • Xiaokang Zhu
    • Xiaoli Ye
    • Xuegang Li

    Original Research 05 September 2012 Pages: 2228 - 2234

18. 3D QSAR studies on 5-(2-methylbenzimidazol-1-yl)-N-alkylthiophene-2-carboxamide derivatives as P. falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitors

    • Vivek K. Vyas
    • Harshang Parikh
    • Manjunath Ghate

    Original Research 06 September 2012 Pages: 2235 - 2243

    

19. Evaluation of the anti-inflammatory activity of some pyrrolo[2,3-d]pyrimidine derivatives

    • Mosaad S. Mohamed
    • Rehab Kamel
    • Rania H. Abd El-hameed

    Original Research 06 September 2012 Pages: 2244 - 2252

    

20. Acid promoted intramolecular formation of 3,5-anhydro-1,4-furano-7-ulose derivatives via the Wittig-cyclization procedure and their antimicrobial properties

    • Fatma Çetin Telli
    • Kadir Ay
    • Yeşim Salman

    Original Research 18 September 2012 Pages: 2253 - 2259

21. Photo-activated metallotherapeutics: copper(I) or silver(I) mixed ligand complexes with 2-mercaptopyrimidine and triphenylphosphine

    • Α. Velalopoulou
    • G. K. Batsala
    • S. K. Hadjikakou

    Original Research 05 September 2012 Pages: 2260 - 2265

    

22. Synthesis, characterization, and antimicrobial activity of some new 2-diazo-benzimidazole derivatives and their Ni(II), Cu(II), and Ag(I) complexes

    • Yellajyosula Lakshmi Narasimha Murthy
    • Guduru Durga
    • Anjali Jha

    Original Research 18 October 2012 Pages: 2266 - 2272

    

23. Inhibition of pancreatic lipase by berberine and dihydroberberine: an investigation by docking simulation and experimental validation

    • Mohammad Mohammad
    • Ihab M. Al-masri
    • Yasser Bustanji

    Original Research 06 September 2012 Pages: 2273 - 2278

    

24. Coumarinyl pyrazole derivatives of INH: promising antimycobacterial agents

    • Prashant Aragade
    • Mahesh Palkar
    • Darbhamulla Satyanarayana

    Original Research 06 September 2012 Pages: 2279 - 2283

    

25. Integrating GUSAR and QSAR analyses for antimalarial activity of synthetic prodiginines against multi drug resistant strain

    • Devidas T. Mahajan
    • Vijay H. Masand
    • Vesna Rastija

    Original Research 22 September 2012 Pages: 2284 - 2292

    

26. 5-Nitro-heteroarylidene analogs of 2-thiazolylimino-4-thiazolidinones as a novel series of antibacterial agents

    • Nouraddin Hosseinzadeh
    • Mohammad Hasani
    • Abbas Shafiee

    Original Research 13 September 2012 Pages: 2293 - 2302

    

27. Pro-apoptotic properties of parthenin analogs: a quantitative structure–activity relationship study

    • Rukmankesh Mehra
    • Amit Nargotra
    • Surrinder Koul

    Original Research 04 October 2012 Pages: 2303 - 2311

    

28. Three-dimensional quantitative structure–activity relationship (3D-QSAR) analysis and molecular docking-based combined in silico rational approach to design potent and novel TRPV1 antagonists

    • Kamlendra Singh Bhadoriya
    • Mukesh C. Sharma
    • Jyotsna R. Rananaware

    Original Research 04 October 2012 Pages: 2312 - 2327

    

29. New molecular scaffolds for the design of Alzheimer’s acetylcholinesterase inhibitors identified using ligand- and receptor-based virtual screening

    • Nitin Chitranshi
    • Shipra Gupta
    • Prahlad Kishore Seth

    Original Research 30 September 2012 Pages: 2328 - 2345

    

30. A new isoflavone from Blepharis ciliaris of an Egyptian origin

    • Mohamed A. El-Shanawany
    • Hanaa M. Sayed
    • Samir A. Ross

    Original Research 18 September 2012 Pages: 2346 - 2350

    

31. Synthesis, physico-chemical properties, and antimicrobial evaluation of a new series of iron(III) hexadentate chelators

    • Yuan-Yuan Xie
    • Mu-Song Liu
    • Tao Zhou

    Original Research 22 September 2012 Pages: 2351 - 2359

    

32. Synthesis, molecular modeling study, preliminary antibacterial, and antitumor evaluation of N-substituted naphthalimides and their structural analogues

    • Adel S. El-Azab
    • Amer M. Alanazi
    • Alaa A.-M. Abdel-Aziz

    Original Research 04 October 2012 Pages: 2360 - 2375

    

33. Synthesis and anticancer evaluation of novel 3,5-diaryl-thiazolo[4,5-d]pyrimidin-2-one derivatives

    • Lilianna Becan
    • Edwin Wagner

    Original Research Open access 04 October 2012 Pages: 2376 - 2384

    

34. Structure–activity relationship study of growth inhibitory 2-styrylchromones against carcinoma cells

    • Chen Lin
    • Pei-Jung Lu
    • Arthur Y. Shaw

    Original Research 23 September 2012 Pages: 2385 - 2394

    

35. Copper(II) complexes with derivatives of pyrazole as potential antioxidant enzyme mimics

    • Bogumiła Kupcewicz
    • Krzysztof Sobiesiak
    • Elżbieta Budzisz

    Original Research Open access 26 September 2012 Pages: 2395 - 2402

    

36. Evidence of stereoselective and segmental-dependant transport of chiral antidiabetic drug nateglinide along the rat small intestine: possible role of efflux transporters

    • Srinivas Maddi
    • Shravan Kumar Yamsani
    • Madhusudan Rao Yamsani

    Original Research 28 September 2012 Pages: 2403 - 2410

    

37. Design and synthesis of niflumic acid-based N-acylhydrazone derivatives as novel anti-inflammatory and analgesic agents

    • Amin Kheradmand
    • Latifeh Navidpour
    • Abbas Shafiee

    Original Research 27 September 2012 Pages: 2411 - 2420

    

38. Synthesis and in vitro anticancer activity of novel thiazacridine derivatives

    • Marina Galdino da Rocha Pitta
    • Érika Silva Souza
    • Ivan da Rocha Pitta

    Original Research 28 September 2012 Pages: 2421 - 2429

    

39. In vivo antidiabetic activity and in silico studies on adenosine monophosphate-activated protein kinase (AMPK) of (2E,5E)-2,5-bis(4-hydroxy-3-methoxybenzylidene) cyclopentanone

    • Chenna Govindaraju Darshan Raj
    • Balladka Kunhanna Sarojini
    • Ramappa Raghavendra

    Original Research 06 October 2012 Pages: 2430 - 2436

    

40. POM analyses of antitrypanosomal activity of 2-iminobenzimidazoles: favorable and unfavorable parameters for drugs optimization

    • Taibi Ben Hadda
    • Rahima Mouhoub
    • Ismail Warad

    Original Research 26 September 2012 Pages: 2437 - 2445

    

41. Synthesis, cytotoxic, and DNA binding studies of novel fluorinated condensed pyrano pyrazoles

    • S. Bhavanarushi
    • V. Kanakaiah
    • J. Vatsala Rani

    Original Research 28 September 2012 Pages: 2446 - 2454

    

42. Synthesis and anticancer activity of para-xylyl linked bis-benzimidazolium salts and respective Ag(I) N-heterocyclic carbene complexes

    • Muhammad Adnan Iqbal
    • Rosenani A. Haque
    • Sawsan S. Al-Rawi

    Original Research 09 October 2012 Pages: 2455 - 2466

    

43. Synthesis, biological evaluation, and molecular modeling studies of new 1,3,4-oxadiazole- and 1,3,4-thiadiazole-substituted 4-oxo-4H-pyrido[1,2-a]pyrimidines as anti-HIV-1 agents

    • Z. Hajimahdi
    • A. Zarghi
    • M. R. Aghasadeghi

    Original Research 28 September 2012 Pages: 2467 - 2475

    

44. Synthesis and QSAR modeling 1-[3-methyl-2-(aryldiazenyl)-2H-aziren-2-yl]ethanones as potential antibacterial agents

    • Vinita Sahu
    • Pratibha Sharma
    • Ashok Kumar

    Original Research 27 September 2012 Pages: 2476 - 2485

    

45. Synthesis of novel 2-phenyl-3-[2-(substituted amino) ethylamino] quinazolin-4(3H)-ones as a new class of H₁-antihistaminic agents

    • V. Alagarsamy
    • P. Shyam Sundar
    • V. Raja Solomon

    Original Research 26 September 2012 Pages: 2486 - 2492

    

46. Computer simulation of the in vitro and in vivo anti-inflammatory activities of dihydropyrimidines acid derivatives through the inhibition of cyclooxygenase-2

    • Raksha Dhankar
    • Anjali M. Rahatgaonkar
    • Ashutosh Tiwari

    Original Research 27 September 2012 Pages: 2493 - 2504

    

47. Synthesis and bioevaluation of novel arylnaphthalene lignans as anticancer agents

    • Yu Zhao
    • Jie Hui
    • Li Zhu

    Original Research 25 September 2012 Pages: 2505 - 2510

    

48. Enhancement of P-gylcoprotein modulators of arylmethylamine-phenyl derivatives: an integrative modeling approach

    • Thirumurthy Madhavan
    • Changdev G. Gadhe
    • Seung Joo Cho

    Original Research 26 September 2012 Pages: 2511 - 2523

    

49. Free radical scavenging and hepatoprotective effects of salidroside analogs on CCl₄-induced cytotoxicity in LO2 cells

    • Yibing Guo
    • Cheng Zheng
    • Yumin Yang

    Original Research 26 September 2012 Pages: 2524 - 2530

    

50. Microbiologically active Mannich bases derived from 1,2,4-triazoles. The effect of C-5 substituent on antibacterial activity

    • Tomasz Plech
    • Monika Wujec
    • Anna Malm

    Original Research Open access 29 September 2012 Pages: 2531 - 2537