1. Preclinical pharmacology of the natural product anticancer agent 10-hydroxycamptothecin, an inhibitor of topoisomerase I

   • Ruiwen Zhang
   • Yufeng Li
   • Brandon Chambless

   ORIGINAL ARTICLE Pages: 257 - 267

2. Metabolism and ribonucleotide reductase inhibition of (E  )-2′-deoxy-2′-(fluoromethylene)cytidine, MDL 101,731, in human cervical carcinoma HeLa S3 cells

   • Takeshi Takahashi
   • Akiko Nakashima
   • Masami Okabe

   ORIGINAL ARTICLE Pages: 268 - 274

3. Effect of 5-aza-2′-deoxycytidine and vitamin D3 analogs on growth and differentiation of human myeloid leukemic cells

   • Benoit T. Doré
   • Christine Chomienne
   • Richard L. Momparler

   ORIGINAL ARTICLE Pages: 275 - 280

4. Phase I clinical and pharmacokinetic study of S9788, a new multidrug-resistance reversal agent given alone and in combination with doxorubicin to patients with advanced solid tumors

   • Brigitte Tranchand
   • Gilles Catimel
   • Claude Ardiet

   ORIGINAL ARTICLE Pages: 281 - 291

5. The antiproliferative action of a melphalan hexapeptide with collagenase-cleavable site

   • F. Timár
   • J. Botyánszki
   • A. Jeney

   ORIGINAL ARTICLE Pages: 292 - 298

6. Quantitation of dolastatin-10 using HPLC/electrospray ionization mass spectrometry: application in a phase I clinical trial

   • D. A. Garteiz
   • T. Madden
   • R. A. Newman

   ORIGINAL ARTICLE Pages: 299 - 306

7. Synergistic cytotoxicity of cisplatin and topotecan or SN-38 in a panel of eight solid-tumor cell lines in vitro

   • Jianguo Ma
   • Marc Maliepaard
   • Jan H. M. Schellens

   ORIGINAL ARTICLE Pages: 307 - 316

8. Distribution of estramustine in the BT4C rat glioma model

   • M. Johansson
   • A. Tommy Bergenheim
   • Roger Henriksson

   ORIGINAL ARTICLE Pages: 317 - 325

9. The antineoplastic ether lipid, s-phosphonate, selectively induces apoptosis in human leukemic cells and exhibits antiangiogenic and apoptotic activity on the chorioallantoic membrane of the chick embryo

   • John K. Jackson
   • Helen M. Burt
   • Ann Marie Oktaba

   ORIGINAL ARTICLE Pages: 326 - 332

10. Cisplatin, epirubicin, and lonidamine combination regimen as first-line chemotherapy for metastatic breast cancer: a pilot study

    • L. Dogliotti
    • S. Danese
    • G. Porcile

    CLINICAL TRIAL REPORT Pages: 333 - 338

11. Length increase of the side chain of idoxifene does not improve its antagonistic potency in breast-cancer cell lines

    • Lu Jin
    • Nicole Legros
    • Michael Jarman

    SHORT COMMUNICATION Pages: 339 - 342

12. Effects of haemopoietic growth factors in combination with etoposide on sister chromatid exchange frequencies in peripheral blood mononuclear cells

    • Wai M. Liu
    • Clare Bamford
    • Simon P. Joel

    SHORT COMMUNICATION Pages: 343 - 346