1. Flavone acetic acid increases the cytotoxicity of mitomycin C when combined with hyperthermia

   • H. Takeuchi
   • Hideo Baba
   • Robert A Newman

   ORIGINAL ARTICLE Pages: 1 - 8

2. Optimal schedule for administering granulocyte colony-stimulating factor in chemotherapy-induced neutropenia in non-small-cell lung cancer

   • Hiroshi Soda
   • M. Oka
   • Kohei Hara

   ORIGINAL ARTICLE Pages: 9 - 12

3. Plasma pharmacokinetics and urinary excretion of the polyamine analogue 1, 19-bis(ethylamino)-5, 10, 15-triazanonadecane in CD2F1 mice

   • J. L. Eiseman
   • Zhi-Min Yuan
   • Merrill J. Egorin

   ORIGINAL ARTICLE Pages: 13 - 20

4. Effects of combined and sequential treatment with tamoxifen and the aromatase inhibitor vorozole on 7,12-dimethylbenz(a) anthracene-induced mammary carcinoma in the rat

   • Robert Van Ginckel
   • Boudewijn Janssens
   • R. De Coster

   ORIGINAL ARTICLE Pages: 21 - 28

5. A novel antitumor compound, NC-190, induces topoisomerase II-dependent DNA cleavage and DNA fragmentation

   • T. Yamagishi
   • Shiro Nakaike
   • Susumu Otomo

   ORIGINAL ARTICLE Pages: 29 - 34

6. Effect of oral chemotherapy on the mitochondrial size of mouse intestinal cells

   • Hanna Bessler
   • Racheli Straussberg
   • Jacob Hart

   ORIGINAL ARTICLE Pages: 35 - 38

7. Imidazoacridinones arrest cell-cycle progression in the G2 phase of L1210 cells

   • E. Augustin
   • Denys N Wheatley
   • J. Konopa

   ORIGINAL ARTICLE Pages: 39 - 44

8. Glutathione S-transferase and glutathione peroxidase are essential in the early stage of Adriamycin resistance before P-glycoprotein overexpression in HOB1 lymphoma cells

   • W.-P. Lee
   • Chao-Lin Lee
   • Hui-Ching Lin

   ORIGINAL ARTICLE Pages: 45 - 51

9. Impact of different fluorouracil biochemical modulators on cellular dihydropyrimidine dehydrogenase

   • M. C. Haaz
   • J. L. Fischel
   • G. Milano

   ORIGINAL ARTICLE Pages: 52 - 58

10. ThioTEPA pharmacokinetics during intravesical chemotherapy: the influence of dose and volume of instillate on systemic uptake and dose rate to the tumour

    • J. R. W. Masters
    • Barbara J McDermott
    • Paul M. Loadman

    ORIGINAL ARTICLE Pages: 59 - 64

11. Trifluoperazine as a modulator of multidrug resistance in refractory breast cancer

    • J. R. Murren
    • Henry J. Durivage
    • William N. Hait

    ORIGINAL ARTICLE Pages: 65 - 70

12. Postlabeling detection of DNA adducts of antitumor alkylating agents

    • Guo-Hao Zhou
    • B. A. Teicher
    • Emil Frei III.

    ORIGINAL ARTICLE Pages: 71 - 80

13. Inhibition of etoposide elimination in the isolated perfused rat liver by Cremophor EL and Tween 80

    • Andrew G. Ellis
    • Nicholas A. Crinis
    • L. K. Webster

    ORIGINAL ARTICLE Pages: 81 - 87

14. Hyaluronidase pretreatment produces selective melphalan enrichment in malignant melanoma implanted in nude mice

    • Ingo Muckenschnabel
    • Günther Bernhardt
    • Armin Buschauer

    ORIGINAL ARTICLE Pages: 88 - 94

15. Doxorubicin-induced cardiotoxicity monitored by ECG in freely moving mice A new model to test potential protectors

    • S. A. B. E. van Acker
    • Klaas Kramer
    • S. A. B. E. van Acker

    ORIGINAL ARTICLE Pages: 95 - 101

16. Intravesical idarubicin: a dose-finding study

    • F. Boccardo
    • D. Cannata
    • Antonio Curotto

    CLINICAL TRIAL REPORT Pages: 102 - 105

17. A weekly alternating chemotherapy regimen with low toxicity for the treatment of aggressive lymphoma

    • M. Bower
    • C. Brock
    • E. S. Newlands

    CLINICAL TRIAL REPORT Pages: 106 - 109

18. Bioavailability of subcutaneous 5-fluorouracil: a case report

    • M. M. Eatock
    • W. Carlin
    • D. G. Watson

    SHORT COMMUNICATION Pages: 110 - 112

19. 6-Mercaptopurine dose escalation and its effect on drug tolerance in childhood lymphoblastic leukaemia

    • J. C. Welch
    • John S. Lilleyman

    SHORT COMMUNICATION Pages: 113 - 116