1. Comparison of the protective effects of desferrioxamine and ICRF-187 against doxorubicin-induced toxicity in spontaneously hypertensive rats

   • E. H. Herman
   • Jun Zhang
   • Victor J. Ferrans

   Original Article Pages: 93 - 100

2. Protein binding of brequinar in the plasma of healthy donors and cancer patients and analysis of the relationship between protein binding and pharmacokinetics in cancer patients

   • Shang-Ying P. King
   • Allison M. Agra
   • Check Y. Quon

   Original Article Pages: 101 - 108

3. Biochemical effects of folate-based inhibitors of thymidylate synthase in MGH-U1 cells

   • Biserka Mitrovski
   • Josie Pressacco
   • Charles Erlichman

   Original Article Pages: 109 - 114

4. Effects of neocarzinostatin upon the development of tumors from murine neuroblastoma cells

   • Patricia Will
   • Kathleen A. Guger
   • Nina Felice Schor

   Original Article Pages: 115 - 120

5. Bioditribution ofO ⁶-benzylguanine and its effectiveness against human brain tumor xenografts when given in polyethylene glycol or cremophor-EL

   • M. Eileen Dolan
   • Anthony E. Pegg
   • Henry S. Friedman

   Original Article Pages: 121 - 126

6. Busulfan therapy of central nervous system xenografts in athymic mice

   • Rosemary H. Aaron
   • Gertrude B. Elion
   • Henry S. Friedman

   Original Article Pages: 127 - 131

7. Depletion of total cysteine, glutathione, and homocysteine in plasma by ifosfamide/mesna therapy

   • Bernhard H. Lauterburg
   • Trinh Nguyen
   • Thomas Cerny

   Original Article Pages: 132 - 136

8. Selective potentiation of platinum drug cytotoxicity in cisplatin-sensitive and-resistant human ovarian carcinoma cell lines by amphotericin B

   • Swee Y. Sharp
   • Prakash Mistry
   • Lloyd R. Kelland

   Original Article Pages: 137 - 143

9. The pharmacokinetics of reduced folates after intraperltoneal and intravenous administration of racemic [6S,R]-folinic acid

   • Jan H. M. Sips
   • Olaf van Tellingen
   • Jos H. Beijnen

   Original Article Pages: 144 - 148

10. Reduced tamoxifen accumulation is not associated with stimulated growth in tamoxifen resistance

    • Juhani Maenpaa
    • Valerie Wiebe
    • Michael DeGregorio

    Original Article Pages: 149 - 152

11. Interaction between endotoxin and the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in the induction of tumour necrosis factor and haemorrhagic necrosis of colon 38 tumours

    • Lai-Ming Ching
    • Wayne R. Joseph
    • Bruce C. Baguley

    Original Article Pages: 153 - 160

12. Phase I study of 5-day continuous infusion fluorodeoxyuridine and high-dose folinic acid with oral hydroxyurea

    • James W. Raschko
    • Steven A. Akman
    • James H. Doroshow

    Original Article Pages: 161 - 164

13. Vincristine with high-dose etoposide in advanced breast cancer: a phase II trial of the Piedmont Oncology Association

    • Gary W. Thomas
    • Hyman B. Muss
    • Robin Heath

    Original Article Pages: 165 - 168

14. Preclinical pharmacology of 1069C85, a novel tubulin binder

    • Florence I. Raynaud
    • Lloyd R. Kelland
    • Ian R. Judson

    Original Article Pages: 169 - 173

15. A phase I/II study of 4′-O-tetrahydropyranyl-doxorubicin, 5-fluorouracil, and high-dose leucovorin as first-line therapy in advanced breast cancer patients

    • Herbert Stöger
    • Thomas Bauernhofer
    • Hellmut Samonigg

    Clinical Trial Report Pages: 174 - 178

16. Validation of a limited sampling model for carboplatin in a high-dose chemotherapy combination

    • Laurence J. C. van Warmerdam
    • Sjoerd Rodenhuis
    • Jos H. Beijnen

    Short Communication Pages: 179 - 181

17. In vitro characterization of the myelotoxicity of cyclopentenyl cytosine

    • Donna A. Volpe
    • De-lin Du
    • Martin J. Murphy Jr.

    Erratum Pages: 182 - 182