1. Brain and plasma pharmacokinetics and anticancer activities of cyclophosphamide and phosphoramide mustard in the rat

   • Shigeru Genka
   • Joseph Deutsch
   • Nigel H. Greig

   Original Articles Pages: 1 - 7

2. Biochemical and pharmacological effects of toremifene metabolites

   • Lauri Kangas

   Original Articles Pages: 8 - 12

3. Studies on the myelosuppressive activity of doxorubicin entrapped in liposomes

   • Marcel B. Bally
   • Rajiv Nayar
   • Lawrence D. Mayer

   Original Articles Pages: 13 - 19

4. Prediction of ACNU plasma concentration-time profiles in humans by animal scale-up

   • Yoshihiro Mitsuhashi
   • Yuichi Sugiyama
   • Tomowo Kobayashi

   Original Articles Pages: 20 - 26

5. Flavone acetic acid and plasma protein binding

   • Joanne Brodfuehrer
   • Frederick Valeriote
   • Thomas Corbett

   Original Articles Pages: 27 - 32

6. Cisplatin preceded by concurrent cytarabine and hydroxyurea: a pilot study based on an in vitro model

   • Kathy S. Albain
   • Lode J. Swinnen
   • Richard I. Fischer

   Original Articles Pages: 33 - 40

7. Mode of action of C-1027, a new macromolecular antitumor antibiotic with highly potent cytotoxicity, on human hepatoma BEL-7402 cells

   • Yong-jie Xu
   • Dian-dong Li
   • Yong-su Zhen

   Original Articles Pages: 41 - 46

8. Comparative effects of doxorubicin and 4′-epi-doxorubicin on nucleic acid metabolism and cytotoxicity in a human tumor cell line

   • Orazio Cantoni
   • Piero Sestili
   • Fernando Giuliani

   Original Articles Pages: 47 - 51

9. A phase II study of ifosfamide and cisplatin chemotherapy for metastatic or relapsed carcinoma of the cervix

   • R. E. Coleman
   • J. M. Clarke
   • P. G. Harper

   Original Articles Pages: 52 - 54

10. Pharmacokinetics of cisplatin given at a daily low dose as a radiosensitiser

    • G. Milano
    • V. Troger
    • J. L. Lagrange

    Original Articles Pages: 55 - 59

11. Biochemical interactions between methotrexate and 1-β-d-arabinofuranosylcytosine in hematopoietic cells of children: a Pediatric Oncology Group study

    • Edward M. Newman
    • Doris G. Villacorte
    • Donald Pinkel

    Original Articles Pages: 60 - 66

12. Comparison of the pharmacokinetics and pharmacodynamics of unformulated and formulated 4-hydroxyandrostenedione taken orally by healthy men

    • M. Dowsett
    • P. Lloyd

    Original Articles Pages: 67 - 71

13. Tumor-tissue and plasma concentrations of platinum during chemotherapy of non-small-cell lung cancer patients

    • Jean-Louis Pujol
    • Didier Cupissol
    • François-Bernard Michel

    Short Communication Pages: 72 - 75

14. Cerebellar toxicity during cytarabine therapy associated with renal insufficiency

    • Henrik Hasle

    Short Communication Pages: 76 - 78

15. A phase II trial of mitomycin C and 5-fluorouracil as second-line therapy in advanced breast cancer

    • Mary E R O'Brien
    • E J Bayliss
    • R C F Leonard

    Short Communication Pages: 79 - 80

16. Meeting announcements

    Announcement Pages: 81 - 81