1. Response to BCNU of spheroids grown from mixtures of drug-sensitive and drug-resistant cells

   • Philip J. Tofilon
   • Carla M. Arundel
   • Dennis F. Deen

   Original Articles Pages: 89 - 95

2. Evaluation of trans-tetrachloro-1,2-diaminocyclohexane platinum (IV) in murine leukemia L1210 resistant and sensitive to cis-diamminedichloroplatinum (II)

   • Lee J. Wilkoff
   • Elizabeth A. Dulmadge
   • Daniel P. Griswold Jr.

   Original Articles Pages: 96 - 100

3. Uridine-induced hypothermia in mice and rats in relation to plasma and tissue levels of uridine and its metabolites

   • G. J. Peters
   • C. J. van Groeningen
   • H. M. Pinedo

   Original Articles Pages: 101 - 108

4. A comparison of adriamycin and mAMSA

   • Catharine M. L. West
   • Ian J. Stratford

   Original Articles Pages: 109 - 114

5. Pharmacokinetics and toxicology of sparsomycin in beagle dogs

   • Zbigniew Zylicz
   • D. J. Theo Wagener
   • Harry C. J. Ottenheijm

   Original Articles Pages: 115 - 124

6. The anti-oestrogen tamoxifen is a calcium antagonist in perfused rat mesentery

   • A. Lipton

   Original Articles Pages: 125 - 127

7. High-dose methotrexate therapy with leucovorin rescue: in vitro investigations on human osteosarcoma cell lines

   • Heyke Diddens
   • Thomas Teufel
   • Dietrich Niethammer

   Original Articles Pages: 128 - 132

8. DNA cross-linking following exposure to cis-platinum in primary and serially passaged cultured cells derived from two murine fibrosarcomas

   • David Murray
   • Ivan Basic
   • Raymond E. Meyn

   Original Articles Pages: 133 - 136

9. Phase I clinical trial of recombinant human tumor necrosis factor

   • Patrick J. Creaven
   • John E. Plager
   • April Proefrock

   Original Articles Pages: 137 - 144

10. Phase I clinical trial of 1-2-[2-(4-pyridyl)-2-imidazoline-1-yl]-ethyl-3-(4-carboxy-phenyl)urea (CGP 15720A)

    • Patrick J. Creaven
    • Stefan Madajewicz
    • M. Kelli Cushman

    Original Articles Pages: 145 - 150

11. (2″-R)-4′-o-Tetrahydropyranyladriamycin, a new anthracycline derivative; its effectiveness in lymphoid malignancies

    • Toshiyuki Takagi
    • Masao Oguro

    Original Articles Pages: 151 - 154

12. Lack of cross-resistance between cytosine arabinoside and a new halogenated nucleoside analogue, 2-bromo-2′-deoxyadenosine in human acute myeloid leukaemia cells

    • Lucia B. Pemble
    • Michelle G. Lihou
    • Peter J. Smith

    Original Articles Pages: 155 - 161

13. Etoposide-induced DNA cleavage in human leukemia cells

    • Catherine M. Edwards
    • Bonnie S. Glisson
    • Warren E. Ross

    Original Articles Pages: 162 - 168

14. A phase I study of trimetrexate, an analog of methotrexate, administered monthly in the form of nine consecutive daily bolus injections

    • Jacques Jolivet
    • Linda Landry
    • Elisabeth Eisenhauer

    Original Articles Pages: 169 - 172

15. Interaction of cimetidine with oral melphalan

    • L. Sviland
    • A. Robinson
    • D. N. Bateman

    Original Articles Pages: 173 - 175

16. Effects of verapamil on the pharmacokinetics of daunomycin in the rat

    • Kees Nooter
    • Robert Oostrum
    • Jan Deurloo

    Short Communication Pages: 176 - 178

17. Etoposide and cisplatinum in resistant lymphomas

    • N. Tubiana
    • C. Lejeune
    • Y. Carcassonne

    Short Communication Pages: 179 - 180

18. Letter to the editors

    • I. R. Judson
    • C. J. Rutty

    Letter Pages: 181 - 182