In this issue (22 articles)

1. Editorial

   Role of heat shock proteins in stress response and carcinogenesis

   C. Cadenas, R. Marchan, H. M. Bolt Pages 1-2

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2. Editorial

   Transcription factors controlling responses to toxic chemicals

   P. Godoy, R. Reif Pages 3-4

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3. Editorial

   Developmental neurotoxicity testing with human embryonic stem cell-derived in vitro systems: the novel FP7 ESNATS tests are available

   H. M. Bolt Pages 5-6

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4. Guest Editorial

   Toxicogenomics for transcription factor-governed molecular pathways: moving on to roles beyond classification and prediction

   Melvin E. Andersen, Patrick D. McMullen, Sudin Bhattacharya Pages 7-11

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5. Guest Editorial

   Stress response pathways, toxicity pathways and adverse outcome pathways

   Paul Jennings Pages 13-14

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6. Guest Editorial

   A new twist to an old tale: novel insights into the differential toxicities of acetaminophen and its regioisomer N-acetyl-meta-aminophenol (AMAP)

   J. Gerry Kenna Pages 15-18

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7. 

   Review Article

   Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update

   Daniel R. Ciocca, Andre Patrick Arrigo, Stuart K. Calderwood Pages 19-48

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8. 

   Review Article

   An overview of transcriptional regulation in response to toxicological insult

   Paul Jennings, Alice Limonciel, Luca Felice, Martin O. Leonard Pages 49-72

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9. Review Article

   Recent trend in risk assessment of formaldehyde exposures from indoor air

   Gunnar Damgård Nielsen, Søren Thor Larsen, Peder Wolkoff Pages 73-98

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10. 

    Inorganic Compounds

    Size of TiO₂ nanoparticles influences their phototoxicity: an in vitro investigation

    Sijing Xiong, Saji George, Zhaoxia Ji, Sijie Lin, Haiyang Yu… Pages 99-109

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11. 

    Toxicokinetics and Metabolism

    The risky cocktail: what combination effects can we expect between ecstasy and other amphetamines?

    Diana Dias da Silva, Helena Carmo, Elisabete Silva Pages 111-122

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12. Toxicogenomics

    Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach

    Anne K. Krug, Raivo Kolde, John A. Gaspar, Eugen Rempel… Pages 123-143

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13. 

    Immunotoxicology

    Assessment of immunotoxicity and genotoxicity in workers exposed to low concentrations of formaldehyde

    Sevtap Aydın, Hande Canpınar, Ülkü Ündeğer, Dicle Güç… Pages 145-153

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14. 

    In vitro systems

    AMAP, the alleged non-toxic isomer of acetaminophen, is toxic in rat and human liver

    Mackenzie Hadi, Sanja Dragovic, Rachel van Swelm, Bram Herpers… Pages 155-165

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15. 

    Organ Toxicity and Mechanisms

    Protection by chrysin, apigenin, and luteolin against oxidative stress is mediated by the Nrf2-dependent up-regulation of heme oxygenase 1 and glutamate cysteine ligase in rat primary hepatocytes

    Chin-Shiu Huang, Chong-Kuei Lii, Ai-Hsuan Lin, Yu-Wen Yeh… Pages 167-178

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16. 

    Genotoxicity and Carcinogenicity

    Genotoxic damage in the oral mucosa cells of subjects carrying restorative dental fillings

    Giuseppa Visalli, Barbara Baluce, Sebastiano La Maestra… Pages 179-187

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17. 

    Genotoxicity and Carcinogenicity

    The impact of FANCD2 deficiency on formaldehyde-induced toxicity in human lymphoblastoid cell lines

    Xuefeng Ren, Zhiying Ji, Cliona M. McHale, Jessica Yuh… Pages 189-196

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18. 

    Biologicals

    Isolation and characterization of two new non-hemorrhagic metalloproteinases with fibrinogenolytic activity from the mapanare (Bothrops colombiensis) venom

    María E. Girón, Alexis Rodríguez-Acosta, Ana María Salazar… Pages 197-208

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19. Short Communication

    Multi-cell type human liver microtissues for hepatotoxicity testing

    S. Messner, I. Agarkova, W. Moritz, J. M. Kelm Pages 209-213

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20. Erratum

    Erratum to: The human bitumen study hits the headlines

    C. Van Thriel, R. Marchan Pages 215-216

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