1. Editorial note

   EditorialNotes Pages: 1 - 1

2. A new inhalation exposure system for the determination of inhaled doses in laboratory rats

   • Carroll A. Snyder
   • Alan B. Bowers

   Original Investigations Pages: 3 - 6

3. Inhalation pharmacokinetics of 1,2-epoxybutene-3 reveal species differences between rats and mice sensitive to butadiene-induced carcinogenesis

   • R. Kreiling
   • R. J. Laib
   • H. M. Bolt

   Original Investigations Pages: 7 - 11

4. Recovery process of tracheal mucosa of guinea pigs exposed to isopropyl alcohol

   • Yoshihiro Ohashi
   • Yoshiaki Nakai
   • Hiroyuki Nakaseko

   Original Investigations Pages: 12 - 20

5. m-Xylene inhalation destroys cytochrome P-450 in rat lung at low exposure

   • Eivor Elovaara
   • Antti Zitting
   • Antero Aitio

   Original Investigations Pages: 21 - 26

6. Interlaboratory comparison of total cytochrome P-450 and protein determinations in rat liver microsomes

   • Alphons A. J. J. L. Rutten
   • Hein E. Falke
   • F. X. Rolaf van Leeuwen

   Original Investigations Pages: 27 - 33

7. Composition of diet modifies toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in cold-adapted rats

   • Giacomo Muzi
   • Joel R. Gorski
   • Karl Rozman

   Original Investigations Pages: 34 - 39

8. Effects of selenium on toxicity and ultrastructural localization of silver in cultured macrophages

   • Jørgen Rungby
   • Svend Ellermann-Eriksen
   • Gorm Danscher

   Original Investigations Pages: 40 - 45

9. Effects of manganese oxide on monkeys as revealed by a combined neurochemical, histological and neurophysiological evaluation

   • Håkan Eriksson
   • Katarina Mägiste
   • Edith Heilbronn

   Original Investigations Pages: 46 - 52

10. Genotoxicity of metacid established through the somatic and germ line mosaic assays and the sex-linked recessive lethal test in drosophila

    • N. K. Tripathy
    • L. Dey
    • C. C. Das

    Original Investigations Pages: 53 - 57

11. iso-OMPA-induced potentiation of soman toxicity in rat

    • Ramesh C. Gupta
    • Wolf -D. Dettbarn

    Original Investigations Pages: 58 - 62

12. Formation of cyanide after i. v. administration of the oxime HI 6 to dogs

    • P. Eyer
    • A. Kawan
    • B. Ladstetter

    Original Investigations Pages: 63 - 69

13. Efficacy of a combination of acetylcholinesterase reactivators, HI-6 and obidoxime, against tabun and soman poisoning of mice

    • John G. Clement
    • J. Deborah Shiloff
    • Chris Gennings

    Original Investigations Pages: 70 - 75

14. Adrenocortical changes and uptake of 4-¹⁴C-corticosterone in rats intoxicated with fenitrothion

    • Anna Osicka-Koprowska
    • Iwona Gradowska-Olszewska
    • Boźena Wysocka-Paruszewska

    Short Communication Pages: 76 - 78

15. Cardiotoxicity testing of organic solvents by coronary artery ligation in closed-chest rats

    • Peter Hoffmann

    Short Communication Pages: 79 - 82

16. Changes in the excretion of endogenous glycine conjugate as a possible artifact in toxicological experiments

    • Igor Linhart
    • Jaroslav Smejkal

    Short Communication Pages: 83 - 85

17. DNA binding assay with 11-aminoundecanoic acid-[11-¹⁴C] in F-344 rats

    • H. Peter
    • U. Föst
    • H. M. Bolt

    Letter to the Editors Pages: 86 - 87